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Copyright: Human Genome Center, Inst. Med. Sci., Univ. Tokyo; 1999-2006
Contact: Kenta Nakai |
| Regulated Operon: | lmrAB |
| Genes | Synonyms | Direction | Genome position | Function | COG ID | Genus clusters |
|---|---|---|---|---|---|---|
| lmrA | lin-2, yccB | - | 289684..290250 | transcriptional regulator | COG1309 | |
| lmrB | yccA | - | 288205..289644 | drug-export protein | COG0477 |
| Operon evidence: | Northern blotting (2.1 kb transcript) |
|---|---|
| Reference: | Yoshida K, et al. (2004), Murata M, et al. (2003), Kumano M, et al. (2003) |
| Comments: | A 0.6/0.7 kb lmrA monocistronic transcript due to a readthrough terminator downstream of lmrA was also found. |
| Binding factor |
Regulation | Location | Absolute position | Binding seq.(cis-element) | Experimental evidence |
|---|---|---|---|---|---|
| LmrA | Negative | -21:+21 | 290272..290313 | TTGAATCAAGATAATAGACCAGTCACTATATTTTTGATTGCA |
Murata M, et al. (2003): DB NB, promoter mutations Yoshida K, et al. (2004): GS DP FT AR, promoter mutations |
| SigA | Promoter | -48:+8 | 290285..290340 | CAATGAATTTTTCTTGACAATTGATGATTGAATCAAGATAATAGACCAGTCACTAT |
Kumano M, et al. (2003): PE |
| Terminator sequence | Absolute position | Position from stop codon | Free energy [kcal/mol] |
Downstream of |
|---|---|---|---|---|
| GAAAAGCCCCTGACTAGTGTTCAGGGGCTTTTTCATGTTTACT >>>>>>>> <<<<<<<< |
lmrB |
|