Regulated Operon: phoPR

Genes
Genes Synonyms Direction Genome position Function COG ID Genus clusters
phoP
- 2976839..2977561 two-component response regulator COG0745 phoP-BAC phoP-STA x1129-BAC  
phoR
- 2975107..2976846 two-component sensor histidine kinase COG0642  

Operon evidence: Northern blotting (2.7 kb transcript)
Reference: Seki T, et al. (1988), Pragai Z, et al. (2004)
Comments:


Promoters

Binding
factor
Regulation Location Absolute position Binding seq.(cis-element) Experimental evidence
CcpA Negative +5:+34 2977703..2977732 TTTACTATAAATGAAAGCGCTATCATAAAC Puri-Taneja A, et al. (2005): DB RG SDM GS FT
PhoP Positive ND 2977766..2977794 TGTCATGAAAGTATTATCCTAATAAAAAG Paul S, et al. (2004): FT RG
PhoP Positive ND 2977658..2977711 ATCATAAACGTCTTTATTTCTTTTAAAAATGATGTAAAAGGCGAATTGTCGGAA Pragai Z, et al. (2004): FT GS
Paul S, et al. (2004): FT RG
PhoP Positive ND 2977600..2977639 ATAAAATCATGAAACATGTTAAGATGACATAAAATAGAGA Pragai Z, et al. (2004): FT GS
PhoP Positive ND 2977494..2977522 ATTGTTACTCTTTTACAGTACAATTTGGA Paul S, et al. (2004): FT RG
ResD Positive ND ND ND Sun G, et al. (1996): DB
SigA Promoter -40:+4 2977627..2977670 CGAATTGTCGGAATGTCCTGCTTTCGCTAAAATAAAATCATGAA Pragai Z, et al. (2004): NB PE
Paul S, et al. (2004): PE, in-vitro reconstitution
SigA Promoter -39:+6 2977605..2977649 TTTCGCTAAAATAAAATCATGAAACATGTTAAGATGACATAAAAT Pragai Z, et al. (2004): NB PE
Paul S, et al. (2004): PE, in-vitro reconstitution
unknown Promoter -47:+5 2977651..2977702 GTCTTTATTTCTTTTAAAAATGATGTAAAAGGCGAATTGTCGGAATGTCCTG Paul S, et al. (2004): PE
SigA Promoter -45:+4 2977733..2977782 ATTATCCTAATAAAAAGAGAGAAAGGCTTGCTTAATACAGCCTTTCTCTT Puri-Taneja A, et al. (2005): PE, in-vitro reconstitution
SigB Promoter -38:+8 2977577..2977622 GTTAAGATGACATAAAATAGAGAAATAGGATGTCGGGGAATTATAA Paul S, et al. (2004): PE, In-vitro reconstitution, DB (unclear result)
SigE Promoter -43:+7 2977593..2977642 AAAATAAAATCATGAAACATGTTAAGATGACATAAAATAGAGAAATAGGA Paul S, et al. (2004): PE, In-vitro reconstitution, DB

Terminator

Terminator sequence Absolute position Position from stop codon Free energy
[kcal/mol]
Downstream of
TTGACGGCGGGAACCTATTTGTGTTCCCGTCCTTTTTTGTGTCTTCT
     >>>>>>>>>        <<<<<<<<<
2974988..2975013
94..119
-16.3
phoR

Overview



Upper Region






Copyright: Human Genome Center, Inst. Med. Sci., Univ. Tokyo; 1999-2006
Contact: Kenta Nakai