Transcription factor: LexA

Factor type UmuD/LexA
SWISS-PROT P31080
SubtiList BG10678
Consensus seq. CGAACATATGTTCG
Comment Negative regulator of DNA damage-inducible genes; SOS-like or SOS regulon; analogue of E. coli LexA
Link to Phylogenetic profile, Weight matrix, Motif alignment & Similar conserved hexameric motifs

Operon Regulated Gene Sigma Regulation Absolute position Location Binding seq.(cis-element) Experimental evidence
aprX aprX SigA Negative 1862069..1862092 -157:-134 TAATACGAACAAACGTTCTTTTTC Au N, et al. (2005): GS AR DB
dinB dinB None Negative 608346..608369 None ACATAAGAACTCATGTTCGTGTAT Cheo DL, et al. (1991): DB RG
Lovett CM Jr, et al (1993): GS
Miller MC, et al. (1996): GS
Winterling KW, et al. (1998): GS
Au N, et al. (2005): GS AR DB
Groban ES, et al. (2005): GS
tagC tagC None Negative 3682365..3682388 None AAAACAGAACAAGTGTTCTTTTTT Raymond-Denise A & Guillen N (1991): DB RG
Cheo DL, et al. (1991): DB RG DP
Lovett CM Jr, et al (1993): GS FT
Miller MC, et al. (1996): GS FT
Winterling KW, et al. (1998): GS
Au N, et al. (2005): GS AR DB
Groban ES, et al. (2005): GS
tagC tagC None Negative 3682395..3682418 None AATACCGAACGTATGTTTGCTTTA Raymond-Denise A & Guillen N (1991): DB RG
Cheo DL, et al. (1991): DB RG DP
Lovett CM Jr, et al (1993): GS FT
Miller MC, et al. (1996): GS FT
Winterling KW, et al. (1998): GS
Au N, et al. (2005): GS AR DB
Groban ES, et al. (2005): GS
dnaE dnaE None Negative 2993712..2993735 None AAAAAAGAACATTTGTTTCTTTTG Le Chatelier E, et al. (2003): DB RG, Western blot
Au N, et al. (2005): GS
hbs hbs None Negative 2385280..2385303 None AAAAAGGAATATTCGTTCGGTAAA Au N, et al. (2005): GS
lexA lexA None Negative 1917519..1917542 -44:-21 TTTTTCGAACCTATGTTTGTACTG Raymond-Denise A & Guillen N (1991): DB RG
Haijema BJ, et al. (1996): DB RG DP GS
Winterling KW, et al. (1998): GS FT
Au N, et al. (2005): GS AR DB
lexA lexA None Negative 1917548..1917571 -72:-49 ATATACGAACAAACGTTTCTGTCA Raymond-Denise A & Guillen N (1991): DB RG
Haijema BJ, et al. (1996): DB RG DP GS
Winterling KW, et al. (1998): GS FT
Au N, et al. (2005): GS AR DB
lexA lexA None Negative 1917585..1917608 -109:-86 CAACAGGAATGTTTGTTCGCATTT Raymond-Denise A & Guillen N (1991): DB RG
Haijema BJ, et al. (1996): DB RG DP GS
Winterling KW, et al. (1998): GS FT
Au N, et al. (2005): GS AR DB
parEC parE None Negative 1932462..1932485 None ATAAACAAACATACGTTCTCATAG Au N, et al. (2005): GS AR DB
pcrBA-ligA-yerH pcrA None Negative 718669..718692 None ATGATAGAACGTATGTTTTGTATA Au N, et al. (2005): GS AR DB
recA recA SigA Negative 1763826..1763849 -60:-37 AAATCCGAATATGCGTTCGCTTTT Raymond-Denise A & Guillen N (1992): DB RG
Lovett CM Jr, et al (1993): GS, promoter mutations
Haijema BJ, et al. (1996): DB GS DP, Western blot
Miller MC, et al. (1996): GS, in-vitro transcription
Winterling KW, et al. (1997): GS RG, promoter mutations
Winterling KW, et al. (1998): GS FT RG, promoter mutation
Hamoen LW, et al. (2001): GS
Au N, et al. (2005): GS AR DB
Groban ES, et al. (2005): GS, promoter mutations
ruvAB ruvA None Negative 2836056..2836079 None AGAAGCGAACATATGTTAACTTTT Au N, et al. (2005): GS AR DB
sda sda SigA Negative 2646548..2646571 -47:-24 ATAACAGAACGATTGTTCTTATAT Au N, et al. (2005): GS
uvrBA uvrB None Negative 3614034..3614057 None ACCACCGAACTTTAGTTCGTATTT Cheo DL, et al. (1991): DB RG DP
Lovett CM Jr, et al (1993): GS
Winterling KW, et al. (1998): GS
Au N, et al. (2005): GS AR DB
Groban ES, et al. (2005): GS
uvrC uvrC None Negative 2911996..2912019 None AGAGAAAAACAAACGTTCGTGTTA Au N, et al. (2005): GS AR DB
vpr vpr None Negative 3906672..3906695 None GTATACGAACGTATATTCCTAACT Au N, et al. (2005): GS
xkdA xkdA None Negative 1320488..1320511 None AAAACAGAACACACGTTCGAAAGG Au N, et al. (2005): GS AR DB
ybaK-cwlD ybaK SigG Negative 155964..155987 -124:-101 ATTACAGAACATTTGTTCCTCACC Au N, et al. (2005): GS AR DB
ydgGH ydgG None Negative 608346..608369 None ATACACGAACATGAGTTCTTATGT Au N, et al. (2005): GS
ydiOP ydiO None Negative 654702..654725 None GATAAAGAACATTCGTTCTTGTAT Au N, et al. (2005): GS AR DB
yhaONM yhaO None Negative 1064086..1064109 None TTGACAGAACGTGCATTCGCAAGA Au N, et al. (2005): GS AR DB
yhaZ yhaZ None Negative 1055558..1055581 None GATCCAGAACGTACATTCCCATAC Au N, et al. (2005): GS AR DB
yhjD yhjD None Negative 1120718..1120741 None CAAATAGAACAAACGTTCCCTTAG Au N, et al. (2005): GS AR DB
yhjE-sipV yhjE None Negative 1120718..1120741 None CTAAGGGAACGTTTGTTCTATTTG Au N, et al. (2005): GS
ykvR ykvR None Negative 1446431..1446453 None TTAACGAACGTATGTTTGTAAAG Au N, et al. (2005): GS
yneAB-ynzC yneA None Negative 1917519..1917542 None CAGTACAAACATAGGTTCGAAAAA Kawai Y, et al. (2003): NB
Au N, et al. (2005): GS AR DB
yneAB-ynzC yneA None Negative 1917548..1917571 None TGACAGAAACGTTTGTTCGTATAT Kawai Y, et al. (2003): NB
Au N, et al. (2005): GS AR DB
yneAB-ynzC yneA None Negative 1917585..1917608 None AAATGCGAACAAACATTCCTGTTG Kawai Y, et al. (2003): NB
Au N, et al. (2005): GS AR DB
yolC yolC None Negative 2271207..2271230 None TTAACAGAACAAACGTTCTTCATT Au N, et al. (2005): GS
yolC yolC None Negative 2271237..2271260 None AAACCAGAACAAAAGTTCGATGTA Au N, et al. (2005): GS
yolD-uvrX yolD None Negative 2271237..2271260 None TACATCGAACTTTTGTTCTGGTTT Au N, et al. (2005): GS
yolD-uvrX yolD None Negative 2271207..2271230 None AATGAAGAACGTTTGTTCTGTTAA Au N, et al. (2005): GS
yorBC yorB None Negative 2187368..2187391 None TAACGAGAACACTTGTTCCCTTTA Au N, et al. (2005): GS
yozLK-yobH yozL None Negative 2064138..2064161 None TACATCGAACTTTTGTTCTGATCT Au N, et al. (2005): GS
yozLK-yobH yozL None Negative 2064108..2064131 None AATAAGGAACGTTTGTTCTGTTGA Au N, et al. (2005): GS
yozM yozM None Negative 2064108..2064131 None TCAACAGAACAAACGTTCCTTATT Au N, et al. (2005): GS
yozM yozM None Negative 2064138..2064161 None AGATCAGAACAAAAGTTCGATGTA Au N, et al. (2005): GS
ypuD ypuD None Negative 2431426..2431449 None AAAACAGAACATAAATTCGTATAT Au N, et al. (2005): GS
yqhB yqhB None Negative 2560683..2560706 None TCCTCCAAACTTTTGTTCTTTATT Au N, et al. (2005): GS
yqjWX yqjW None Negative 2465027..2465050 None TAAAACGAACATACTTTCGCATAT Au N, et al. (2005): GS AR DB
yqjWX yqjW None Negative 2464999..2465022 None AAAAGCGAACATAAGTTCTTTTTA Au N, et al. (2005): GS AR DB
yqxL yqxL SigB Negative 2560683..2560706 None AATAAAGAACAAAAGTTTGGAGGA Au N, et al. (2005): GS
yqzH yqzH None Negative 2465027..2465050 None ATATGCGAAAGTATGTTCGTTTTA Au N, et al. (2005): GS
yqzH yqzH None Negative 2464999..2465022 None TAAAAAGAACTTATGTTCGCTTTT Au N, et al. (2005): GS




Copyright: Human Genome Center, Inst. Med. Sci., Univ. Tokyo; 1999-2006
Contact: Kenta Nakai