Regulated Operon: groESL

Genes
Genes Synonyms Direction Genome position Function COG ID Conserved groups
groES
+ 649903..650187
COG0234O groES-BAC groES-STA  
groEL
+ 650234..651868
COG0459O groEL-BAC groEL-STA  

Operon evidence: Northern blotting (2.1 kb transcript)
Reference: Li M & Wong SL (1992), Ohshima H, et al. (2002)
Comments: Oshima found a 7.6 kb groESL-ydiNOP readthrough transcript induced by heat treatment.


Promoters

Binding
factor
Regulation Location Absolute position Binding seq.(cis-element) Experimental evidence
HrcA Negative +5:+31 649841..649867 TTAGCACTCTTTAGTGCTGAGTGCTAA Hecker M, et al. (1996): HB GS
Voelker U, et al. (1994): 2D PAGE, HB
SigA Promoter -43:+18 649794..649854 CTTATCACTTGAAATTGGAAGGGAGATTCTTTATTATAAGAATTGTGTTAGCACTCTTTAG Li M, et al. (1992): PE

Terminator

Terminator sequence Absolute position Position from stop codon Free energy
[kcal/mol]
Downstream of
GAGAAGGTCTTTCATCAGTTTACTAAACTGTTGGGAGACCTTTTCTCCATATTAG
     >>>>>>>>>>>>>>>>   <<<<<<<<<<<<<<<<
651947..651981
79..113
-20.0
groEL

Overview



Upper Region






Copyright: Human Genome Center, Inst. Med. Sci., Univ. Tokyo; 1999-2008
Contact: Kenta Nakai