Transcription factor: GltC

Factor type LysR
SWISS-PROT P20668
SubtiList BG10810
Consensus seq. ATCTCAN3TGAGAT, ATCTAAN3ATATAT
Comment Like many members of LysR family, GltC is encoded just upstream of and in the opposite orientation to its target genes (gltAB)
it negatively autoregulates itself
The binding site for the autoregulation is the same with the box I of gltA (-71:-57) in its genome position
Box II of gltA overlaps with its -35 region
cf. GltR
Link toPhylogenetic profile , Weight matrix & Motif alignment

Regulated
gene
Operon Sigma Regulation Absolute position Location Binding seq.(cis-element) Exp. Reference Year
gltA glutamate synthase operon ND Positive 2013955..2013969 -71:-57 ATCTCATTTTGAGAT
SDM DP Belitsky BR, et al. 1995
gltA glutamate synthase operon ND Positive 2013933..2013947 -49:-35 ATCTAAATTATATAT
SDM DP Belitsky BR, et al. 1995
gltC glutamate synthase operon ND Negative 2013955..2013969 +5:+19 ATCTCAAAATGAGAT
SDM DP Belitsky BR, et al. 1995




Copyright: Human Genome Center, Inst. Med. Sci., Univ. Tokyo; 1999-2004
Contact: knakai@ims.u-tokyo.ac.jp