Transcription factor: RocR

Factor type NtrC/NifA
SWISS-PROT P38022
SubtiList BG10723
Consensus seq. GCAAAATAATTTTGCA(T/C)T
Comment NtrC/NifA transcriptional activator (cf. LevR)
sigma 54-dependent activators generally bind two inverted repeat sequences called UAS, which are located approx. 100bp upstream from the -12/-24 promoters
DNA bending is used for activation (AhrC may be involved)
inducible by ornithine or citrulline?
at least upstream UAS1 is the target of RocR
Link toPhylogenetic profile , Weight matrix & Motif alignment

Regulated
gene
Operon Sigma Regulation Absolute position Location Binding seq.(cis-element) Exp. Reference Year
rocA rocABC SigL Positive 3879729..3879752 -217:-194 CCTCCGCAAAATAATTTTGCATTT
FT
DP DB
Ali, N. O., et al.
Calogero S, et al.
2003
1994
rocA rocABC SigL Positive 3879680..3879708 -173:-145 AAAACGCAAAATAAATTTGCGTTCAAGAT
FT
DP DB
Ali, N. O., et al.
Calogero S, et al.
2003
1994
rocD rocDEF SigL Positive 4144687..4144707 -130:-110 TATGCAAAAGAATTTTGCACT
DP HM Gardan R, et al. 1995
rocD rocDEF SigL Positive 4144646..4144666 -89:-69 ATATCAGAATGTTTTTGCACC
DP HM Gardan R, et al. 1995
rocG rocG SigL Positive ND DAS(Downstream activating sequence)
GS FT Belitsky BR, et al.
Ali, N. O., et al.
1999
2003
rocR rocR SigA Negative 4144687..4144707 -30:-50 TATGCAAAAGAATTTTGCACT
DB PE Gardan R, et al. 1995




Copyright: Human Genome Center, Inst. Med. Sci., Univ. Tokyo; 1999-2004
Contact: knakai@ims.u-tokyo.ac.jp