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Copyright: Human Genome Center, Inst. Med. Sci., Univ. Tokyo; 1999-2006
Contact: Kenta Nakai |
| Regulated Operon: | lytABC |
| Genes | Synonyms | Direction | Genome position | Function | COG ID | Genus clusters |
|---|---|---|---|---|---|---|
| lytA | lppX | - | 3661819..3662127 | membrane bound lipoprotein | ||
| lytB | cwbA | - | 3659678..3661795 | modifier protein of major autolysin LytC (CWBP76) | COG2385 | |
| lytC | cwlB | - | 3658149..3659639 | N-acetylmuramoyl-L-alanine amidase (major autolysin) (CWBP49) | COG0860 |
| Operon evidence: | Northern blotting (4.1 kb transcript measured by Kuroda; 4.0 kb transcript measured by Serizawa) |
|---|---|
| Reference: | Lazarevic V, et al. (1992), Kuroda A & Sekiguchi J (1993), Serizawa M, et al. (2005), Genbank M87645 |
| Comments: | Shorter transcripts were also detected. |
| Binding factor |
Regulation | Location | Absolute position | Binding seq.(cis-element) | Experimental evidence |
|---|---|---|---|---|---|
| LytR | Negative | ND | ND | ND |
Lazarevic V, et al. (1992): DB Serizawa M, et al. (2005): RG |
| SigA | Promoter | -39:+7 | 3662154..3662199 | AGTTTCATTGTTTCTTAATTTTTCTTTAAAATATAAAATAGGTTGA |
Lazarevic V, et al. (1992): PE |
| SigD | Promoter | -42:+7 | 3662133..3662181 | TTTTTCTTTAAAATATAAAATAGGTTGACGATAAAATATAATGAGGTGA |
Lazarevic V, et al. (1992): PE DB Kuroda A & Sekiguchi J (1993): PE RG |
| YvrH | Negative | ND | ND | ND |
Serizawa M, et al. (2005): NB DB AR RG |
| Terminator sequence | Absolute position | Position from stop codon | Free energy [kcal/mol] |
Downstream of |
|---|---|---|---|---|
| CGAAAGAGACAAATCTAATCACAGATTTGTCTCTTTTTTATATGAAAT >>>>>>>>>>> <<<<<<<<<<< |
lytC |
|