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Copyright: Human Genome Center, Inst. Med. Sci., Univ. Tokyo; 1999-2006
Contact: Kenta Nakai |
| Regulated Operon: | nadBCA |
| Genes | Synonyms | Direction | Genome position | Function | COG ID | Genus clusters |
|---|---|---|---|---|---|---|
| nadB | - | 2847096..2848691 | L-aspartate oxidase | COG0029 | ||
| nadC | yrxB | - | 2846273..2847142 | nicotinate-nucleotide pyrophosphorylase | COG0157 | |
| nadA | - | 2845180..2846286 | quinolinate synthetase | COG0379 | nadA-BAC |
| Operon evidence: | insertional plasmid |
|---|---|
| Reference: | Sun D & Setlow P (1993), Rossolillo P, et al. (2005) |
| Comments: | Experimental evidence showed that nadB and nadC are in the same operon; no experimental evidence for nadA |
| Binding factor |
Regulation | Location | Absolute position | Binding seq.(cis-element) | Experimental evidence |
|---|---|---|---|---|---|
| SigA | Promoter | -47:+16 | 2848707..2848769 | ATAAAAAACTCTTGAGTTTATTTTATCCTTGTGTAAATATAGGTGTCAAGACAGGTGTAAACA |
Sun D & Setlow P (1993): PE |
| YrxA | Negative | -74:+34 | 2848689..2848796 | CATCCGGTCTTCCTCCATCCGTTCTCCATAAAAAACTCTTGAGTTTATTTTATCCTTGTGTAAATATAGGTGTCAAGACAGGTGTAAACAACAGGAGGATGGCATATG |
Sun D & Setlow P (1993): HM Rossolillo P, et al. (2005): GS RT-PCR |
| Terminator sequence | Absolute position | Position from stop codon | Free energy [kcal/mol] |
Downstream of |
|---|---|---|---|---|
| TGAATCGAATGCTTTCGATCACGTAGATCAGAAATATTTTCCCTTCCTTTA >>>>>>>> <<<<<<<<< |
nadA |
|