Regulated Operon: purA

Genes
Genes Synonyms Direction Genome position Function COG ID Genus clusters
purA
- 4154457..4155749 adenylosuccinate synthetase COG0104 purA-BAC purA-STA purA-STR  

Operon evidence: Northern blotting (1.40 kb transcript)
Reference: Mantsala P & Zalkin H (1992), Nickel M, et al. (2004)
Comments:


Promoters

Binding
factor
Regulation Location Absolute position Binding seq.(cis-element) Experimental evidence
PurR Negative -88:-35 4155828..4155881 GAATGGAAGCGAACGAATATAGATTTACAATAAATTAATGTTCGGATTTACAAT Saxild HH & Nygaard P (1991): Enzyme activity measurement
Weng M, et al. (1995): GS
Shin BS, et al. (1997): GS FT
Rappu P, et al. (1999): RG DP DB
Saxild HH, et al. (2001): HM
Rappu P, et al. (2005): RG SDM GS
SigA Promoter -46:+18 4155776..4155839 CGGATTTACAATTGACTTTCTGTTTCTTCACTGATAAACTTGATTTGTTTGAATAGAATCGTTT Mantsala P, et al. (1992): PE

Terminator

Terminator sequence Absolute position Position from stop codon Free energy
[kcal/mol]
Downstream of
GTCTGCAAGCCCCTATTTAAGGGGCTTGTTTTTTGTTTGAAAG
     >>>>>>>>>     <<<<<<<<<
4154420..4154442
15..37
-17.8
purA

Overview



Upper Region






Copyright: Human Genome Center, Inst. Med. Sci., Univ. Tokyo; 1999-2006
Contact: Kenta Nakai