Regulated operon: comK

Regulated Operon:

comK

Genes

Genes	Synonyms	Direction	Genome position	Function	COG ID	Conserved groups
comK		+	1117109..1117687		COG4903K	x1066-BAC

Operon evidence:	Genome analysis; upstream and downstream gene are on the opposite strand
Reference:	Van Sinderen D, et al. (1994)
Comments:

Promoters

Binding factor	Regulation	Location	Absolute position	Binding seq.(cis-element)	Experimental evidence
AbrB	Negative	`-81:+39`	1116992..1117111	`CATTAAATATCATTAAAAGATGATTTTATCTTAAATGTTAAAAAAACCTGTCGTTTTACAAAAACAGATGATAGATTATTAGTATAAATTTTGCAGAAAAAGGATGGAGGCCATAATATG`	Hamoen LW, et al. (2003): FT Hahn J, et al. (1994): DB
CodY	Negative	`-77:-13`	1116996..1117060	`AAATATCATTAAAAGATGATTTTATCTTAAATGTTAAAAAAACCTGTCGTTTTACAAAAACAGAT`	Serror P, et al. (1996): DB FT GS
ComK	Positive	`-118:-83`	1116955..1116990	`TGAAAGTAAAATCGGTTTATTACTAGTCATTTAGTA`	Van Sinderen D & Venema G (1994): RG OV DB; Western blot Van Sinderen D, et al. (1995): GS Hamoen LW, et al. (1998): FT Berka RM, et al. (2002): AR HM
ComK	Positive	`-83:-55`	1116990..1117018	`ACCATTAAATATCATTAAAAGATGATTTT`	Van Sinderen D & Venema G (1994): RG OV DB; Western blot Van Sinderen D, et al. (1995): GS Hamoen LW, et al. (1998): FT Berka RM, et al. (2002): AR HM
DegU	Positive	`-102:-73`	1116971..1117005	`TTATTACTAGTCATTTAGTACCATTAAATATCATT`	Hahn J, et al. (1994): DB Van Sinderen D & Venema G (1994): RG DB; Western blot Ogura M, et al. (1996): DB RG Hamoen LW, et al. (2000): GS FT Shimane K & Ogura M (2004): SDM RG
Med	Positive	ND	ND	ND	Ogura M, et al. (1997): DP
Rok	Negative	ND	ND	ND	Hoa TT, et al. (2002): GS DB RG OV Albano M, et al. (2005): GS
SigA	Promoter	`-49:+20`	1117024..1117092	`AAATGTTAAAAAAACCTGTCGTTTTACAAAAACAGATGATAGATTATTAGTATAAATTTTGCAGAAAAA`	Van Sinderen D, et al. (1994): PE
Spo0A	ND	ND	ND	ND	Molle V, et al. (2003): GS CH

Terminator

Terminator sequence	Absolute position	Position from stop codon	Free energy [kcal/mol]	Downstream of
`ATTAGAAAAATAGGAAGGAGCTGACCGAACAGGGCAGCTCCTTTCATAAAGCTATG >>>>>>>>>> <<<<<<<<<<`	1117699..1117723	12..36	-16.7	comK

Overview

Upper Region

Copyright: Human Genome Center, Inst. Med. Sci., Univ. Tokyo; 1999-2008
Contact: Kenta Nakai