Transcription factor: SigM

Factor type ND
SWISS-PROT ND
SubtiList ND
Consensus seq. ND
Comment Essential for growth and survival in high concentrations of salt; expression positively autoregulated through a sigma-M promoter; expression maximal during exponential growth and increased in high concentrations of salt; activity negatively regulated by YhdL and YhdK
Link to Phylogenetic profile

Operon Regulated Gene Absolute position Location Binding seq.(cis-element) Experimental evidence
sigM-yhdLK sigM 1030083..1030126 -40:+4 GTAATGTGCAACTTTAAACCTTTCTTATGCGTGTATAACATAGA Horsburgh MJ & Moir A (1999): PE DB NB RG
Cao M, et al. (2002): AR
yqjL yqjL ND ND ND Cao M, et al. (2005): RG DB
Cao M, et al. (2002): AR
ywoA ywoA 3758484..3758527 -38:+6 TTATTTGAAACTTTTCATGAGTAAGATTAGTCTACTAAATATAA Cao M & Helmann JD (2002): HB PE DB RG
Cao M, et al. (2002): AR
Ohki R, et al. (2003): NB RG DB
Thackray PD, et al. (2003): RG
Mascher T, et al. (2003): HB
yjbCD yjbD 1227524..1227583 -50:+10 TAAGAACATATCATGAACATTAAAAATTTGCTGGATTGACACATTTTTTTCTTAGGATAC Leelakriangsak M, et al. (2007): ND
Thackray PD, et al. (2003): RG
yrhIJ yrhJ ND ND ND Thackray PD, et al. (2003): RG
radC radC ND ND ND Thackray PD, et al. (2003): RG
yra yraA ND ND ND Thackray PD, et al. (2003): RG




Copyright: Human Genome Center, Inst. Med. Sci., Univ. Tokyo; 1999-2008
Contact: Kenta Nakai