Regulated Operon: eps

Genes
Genes Synonyms Direction Genome position Function COG ID Genus clusters
yveK epsA - 3528181..3528885
COG3944  
yveL epsB - 3527492..3528175
COG0489  
yveM epsC - 3525437..3527233
COG1086  
yveN epsD - 3524280..3525425
COG0438  
yveO epsE - 3523447..3524283
COG0463  
yveP epsF - 3522300..3523454
COG0438  
yveQ epsG - 3521200..3522303

 
yveR epsH - 3520141..3521175
COG0463  
yveS epsI - 3519060..3520136
COG5039  
yveT epsJ - 3518029..3519063
COG0463  
yvfA epsK - 3517703..3518032

 
yvfB epsK - 3516516..3517553

 
yvfC epsL - 3515911..3516519
COG2148 yvfC-LAC  
yvfD epsM - 3515264..3515914
COG0110 yvjF-LAC  
yvfE epsN - 3514093..3515259

 
yvfF epsO - 3513146..3514114
COG5039  

Operon evidence: Genome analysis. Transcriptional fusions of lacZ to the yveK and yveM upstream regions indicate that yveM does not have its own promoter (D. Kearns, personal communication). However, Northern blotting experiments by Yoshida show a 1.2 kb yveKL transcript, which may be due to a readthrough terminator downstream of yveL. Note that yvfA and yvfB constitute one gene (epsK); this gene is listed as two ORFs due to a sequencing error (Kearns et al).
Reference: Yoshida K, et al. (2003), Kearns DB, et al. (2005)
Comments:

Promoters

Binding
factor		 Regulation Location Absolute position Binding seq.(cis-element) Experimental evidence
SigA Promoter -43:+6 3528936..3528985 TTTTGCAATTTTTAAATAATAACGTTTTCTTTTATAATCCAATCATTAAC Kearns DB, et al. (2005): PE
SinR Negative -163:-124 3529066..3529105 TCGTTATTTCGTTCATTATAAGGAATTTTTCGTTCTTTAT Kearns DB, et al. (2005): GS FT RG
SinR Negative -73:-48 3528990..3529015 TTTGTTCTCTAAAGAGAACTTATTGG Kearns DB, et al. (2005): GS FT RG

Terminator

No Data

Overview



Upper Region
Copyright: Human Genome Center, Inst. Med. Sci., Univ. Tokyo; 1999-2006
Contact: Kenta Nakai