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Copyright: Human Genome Center, Inst. Med. Sci., Univ. Tokyo; 1999-2006
Contact: Kenta Nakai |
| Regulated Operon: | groESL |
| Genes | Synonyms | Direction | Genome position | Function | COG ID | Genus clusters |
|---|---|---|---|---|---|---|
| groES | + | 649450..649734 | class I heat-shock protein (chaperonin) | groES-BAC groES-STA | ||
| groEL | + | 649781..651415 | class I heat-shock protein (chaperonin) | COG0459 | groEL-BAC groEL-STA |
| Operon evidence: | Northern blotting (2.1 kb transcript) |
|---|---|
| Reference: | Li M & Wong SL (1992), Ohshima H, et al. (2002) |
| Comments: | Oshima found a 7.6 kb groESL-ydiNOP readthrough transcript induced by heat treatment. |
| Binding factor |
Regulation | Location | Absolute position | Binding seq.(cis-element) | Experimental evidence |
|---|---|---|---|---|---|
| HrcA | Negative | +5:+31 | 649388..649414 | TTAGCACTCTTTAGTGCTGAGTGCTAA |
Hecker M, et al. (1996): HB GS Voelker U, et al. (1994): 2D PAGE, HB |
| SigA | Promoter | -43:+18 | 649341..649401 | CTTATCACTTGAAATTGGAAGGGAGATTCTTTATTATAAGAATTGTGTTAGCACTCTTTAG |
Li M, et al. (1992): PE |
| Terminator sequence | Absolute position | Position from stop codon | Free energy [kcal/mol] |
Downstream of |
|---|---|---|---|---|
| GAGAAGGTCTTTCATCAGTTTACTAAACTGTTGGGAGACCTTTTCTCCATATTAG >>>>>>>>>>>>>>>> <<<<<<<<<<<<<<<< |
groEL |
|