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Copyright: Human Genome Center, Inst. Med. Sci., Univ. Tokyo; 1999-2006
Contact: Kenta Nakai |
| Regulated Operon: | hemAXCDBL |
| Genes | Synonyms | Direction | Genome position | Function | COG ID | Genus clusters |
|---|---|---|---|---|---|---|
| hemA | - | 2876831..2878198 | glutamyl-tRNA reductase | COG0373 | hemA-BAC-1 hemA-BAC-2 hemA-STA | |
| hemX | - | 2875993..2876823 | membrane-bound protein | COG0755 | hemX-STA | |
| hemC | - | 2875016..2875960 | porphobilinogen deaminase (hydroxymethylbilane synthase) | COG0181 | hemC-BAC-1 hemC-BAC-2 hemC-STA | |
| hemD | - | 2874238..2875026 | uroporphyrinogen III cosynthase | COG1587 | ||
| hemB | - | 2873267..2874241 | delta-aminolevulinic acid dehydratase (porphobilinogen synthase) | COG0113 | ||
| hemL | hemK | - | 2871945..2873237 | glutamate-1-semialdehyde 2,1-aminotransferase | COG0001 | x0761-STA |
| Operon evidence: | genetic modification of hemL |
|---|---|
| Reference: | Hansson M, et al. (1991) |
| Comments: |
| Binding factor |
Regulation | Location | Absolute position | Binding seq.(cis-element) | Experimental evidence |
|---|---|---|---|---|---|
| PerR | Negative | ND | 2878259..2878287 | AGAAACTATGTTATAATTATTATAAATAA |
Herbig AF, et al. (2001): FT |
| PerR | Negative | ND | 2878213..2878254 | TTCTATGTTAGAATGATTATAAATTAAGATTGGGTGTTGGGG |
Herbig AF, et al. (2001): FT |
| SigA | Promoter | ND | 2878247..2878314 | TTTTAAAATCTGTTCACATTTTGTGAAAGAAACTATGTTATAATTATTATAAATAATGAGTTCTATGT |
Hansson M, et al. (1991): S1 |
| Terminator sequence | Absolute position | Position from stop codon | Free energy [kcal/mol] |
Downstream of |
|---|---|---|---|---|
| GAAAACCGGTATCAAGGACTCCTTGTGCCGGTTTTTTCGTGCTCTC >>>>>>>>>>>> <<<<<<<<<<< |
hemL |
|