Transcription factor: PerR

Factor type	ND
SWISS-PROT	P71086
SubtiList	BG12227
Consensus seq.	TTATAATNATTATAA
Comment	transcription induced by hydrogen peroxide, by general stress, or by entry into stationary phase under conditions of iron and manganese limitation (class III stress response); expression modulated by Ca2+; mutants lead to higher expression from all peroxide regulon promoters (mrgA, katA, hemAXCDBL, and ahpCF), but has no effect on spore resistance to alkyl hydroperoxides, heat or hydrogen peroxide
Link to	Phylogenetic profile, Weight matrix, Motif alignment & Similar conserved hexameric motifs

Operon	Regulated Gene	Sigma	Regulation	Absolute position	Location	Binding seq.(cis-element)	Experimental evidence
ahpCF	ahpC	SigA	Negative	`4117874..4117935`	`-36:+26`	CTTGACAAAAAATATATATTAATTAATAATTCATATATAATTAGAATTATTATTGAAAGCGA	Herbig AF, et al. (2001): FT
fur	fur	SigA	Negative	`2449534..2449566`	`-61:-29`	TTATTTATCAGTTTATAATAATTATAGTTGGAA	Fuangthong M, et al. (2002): FT
hemAXCDBL	hemA	SigA	Negative	`2878259..2878287`	None	AGAAACTATGTTATAATTATTATAAATAA	Herbig AF, et al. (2001): FT
hemAXCDBL	hemA	SigA	Negative	`2878213..2878254`	None	TTCTATGTTAGAATGATTATAAATTAAGATTGGGTGTTGGGG	Herbig AF, et al. (2001): FT
katA	katA	None	Negative	`960348..960405`	None	CTATTTTATAATAATTATAAAATAATATTGACTTTTTACTTAGAGATGATATTATGTT	Herbig AF, et al. (2001): FT Engelmann S, et al. (1995): NB Bol DK & Yasbin RE (1994): RG HB PE
mrgA	mrgA	SigA	Negative	`3382504..3382557`	`-60:-7`	CTAAATTATAATTATTATAATTTAGTATTGATTTTTATTTAGTATATGATATAA	Herbig AF, et al. (2001): FT
srfAA-srfAB-comS-srfAC-srfAD	srfAA	SigA	Positive	`376072..376122`	`-163:-113`	TTTAAAAATTTTTATTTTTCTGTAAATAATGTTTAGTGGAAATGATTGCGG	Hayashi K, et al. (2005): GS FT
perR	perR	SigA	Negative	`943762..943787`	`-13:+13`	TTACACTAATTATAAACATTACAATG	Fuangthong M, et al. (2002): FT
perR	perR	SigA	Negative	`943771..943793`	`-4:+18`	TTATAAACATTACAATGTAAGAA	Fuangthong M, et al. (2002): FT
ykvW	ykvW	SigA	Negative	`1450497..1450547`	`-75:-25`	TAATGATAATTATTATCAAAAAGAAATTAAAATAATTATAATTGAAATTCT	Gaballa A, et al. (2002): FT
yjbCD	yjbD	None	Negative	`1226892..1226971`	`-40:+40`	GATACTGTTCACACTTACTTTTTTATAGTATAATACCTGTAAAGATTCCTTTTTTAGAGTAATTTCAATTTAAGAATAAA	Leelakriangsak M, et al. (2007): FT