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Copyright: Human Genome Center, Inst. Med. Sci., Univ. Tokyo; 1999-2006
Contact: Kenta Nakai |
| Regulated Operon: | nprE |
| Genes | Synonyms | Direction | Genome position | Function | COG ID | Genus clusters |
|---|---|---|---|---|---|---|
| nprE | - | 1539343..1540908 | extracellular neutral metalloprotease | COG3227 |
| Operon evidence: | Genome analysis |
|---|---|
| Reference: | Genbank AF012285 |
| Comments: |
| Binding factor |
Regulation | Location | Absolute position | Binding seq.(cis-element) | Experimental evidence |
|---|---|---|---|---|---|
| DegU | Positive | ND | ND | ND |
Kunst F, et al. (1974): neutral protease activity; DB Ayusawa D, et al. (1975): protease activity; DB Yoneda Y & Maruo B (1975): neutral protease activity; DB Tanaka T & Kawata M (1988): neutral protease activity; DB |
| Hpr | Negative | -107:-82 | 1541024..1541049 | CTTGATATTATTCAACAAAAACAAAC |
Higerd TB, et al. (1972): neutral protease activity Kallio PT, et al. (1991): GS FT |
| Hpr | Negative | -26:-4 | 1540946..1540968 | GAATGCTAGTTTAATATAACAAT |
Higerd TB, et al. (1972): neutral protease activity Kallio PT, et al. (1991): GS FT |
| PaiA | Negative | ND | ND | ND |
Honjo M, et al. (1990): DB HB |
| PaiB | Negative | ND | ND | ND |
Honjo M, et al. (1990): DB HB |
| TenA | Positive | ND | ND | ND |
Pang AS, et al. (1991): DB |
| Terminator sequence | Absolute position | Position from stop codon | Free energy [kcal/mol] |
Downstream of |
|---|---|---|---|---|
| GAAAAGCCTGAGATCCCTCAGGCTTTTATTGTTACATA >>>>>>> <<<<<<< |
nprE |
|