Transcription factor: DegU

Factor type LuxR/UhpA family
SWISS-PROT P13800
SubtiList BG10393
Consensus seq. TAAAT
Comment pleiotropic regulator involved in various post-exponential phase responses; makes a two component system with DegS kinase
Link to Phylogenetic profile, Weight matrix, Motif alignment & Similar conserved hexameric motifs

Operon Regulated Gene Sigma Regulation Absolute position Location Binding seq.(cis-element) Experimental evidence
amyE amyE SigA Positive ND ND ND Ayusawa D, et al. (1975): amylase activity; DB
Yoneda Y & Maruo B (1975): amylase activity; DB
Steinmetz M, et al. (1976): amylase activity; DB
aprE aprE SigA Positive 1104949..1105008 -83:-24 GATATACCTAAATAGAGATAAAATCATCTCAAAAAAATGGGTCTACTAAAATATTATTCC Kunst F, et al. (1974): serine protease activity; DB
Ayusawa D, et al. (1975): protease activity; DB
Yoneda Y & Maruo B (1975): serine protease activity; DB
Ferrari E, et al. (1986): DB RG
Tanaka T & Kawata M (1988): serine protease activity; DB
Henner DJ, et al. (1988): Genetics and biotechnology of Bacilli, vol.2 pp.3-9: DP RG
Mukai K, et al. (1992): DP DB OV RG
Ogura M, et al. (2003): RG DB GS
Shimane K & Ogura M (2004): SDM DB RG
licT-bglS bglS SigA Positive ND ND ND Aymerich S et al. (1986): DB, glucanase activity
comK comK SigA Positive 1116275..1116309 -102:-73 TTATTACTAGTCATTTAGTACCATTAAATATCATT Hahn J, et al. (1994): DB
Van Sinderen D & Venema G (1994): RG DB; Western blot
Ogura M, et al. (1996): DB RG
Hamoen LW, et al. (2000): GS FT
Shimane K & Ogura M (2004): SDM RG
degQ degQ SigA Positive ND ND ND Msadek T, et al. (1990): DB RG
Msadek T, et al. (1991): DP DB RG
ispA ispA SigA Positive ND ND ND Ruppen ME, et al. (1988): DB RG, protease activity
nprE nprE SigA Positive ND ND ND Kunst F, et al. (1974): neutral protease activity; DB
Ayusawa D, et al. (1975): protease activity; DB
Yoneda Y & Maruo B (1975): neutral protease activity; DB
Tanaka T & Kawata M (1988): neutral protease activity; DB
sacB-yveBA sacB SigA Positive ND ND ND Kunst F, et al. (1974): levansucrase activity; DB
Steinmetz M, et al. (1976): levansucrase activity; DB
Chambert R & Petit-Glatron MF (1984): levansucrase activity; SDS-PAGE DB
Aymerich S et al. (1986): RG DB dot-blot
Shimotsu H & Henner DJ (1986): S1 RG DB
Klier A et al. (1987): levansucrase activity, DB DP
Henner DJ, et al. (1988): Genetics and biotechnology of Bacilli, vol.2 pp.3-9: DP RG
sacXY sacX SigA Positive 3940856..3940912 -112:-56 GTCTTAAAGGTTTTTTTCATTCTAAGAACACCACACACAACCTTTTTCCCATCCATT Crutz AM & Steinmetz M (1992): DB RG DP
sipS sipS None Positive 2432720..2432740 -648:-628 GATGTAATGAAAAGGAGATCG Bolhuis A, et al. (1996): DB OV RG NB
Tjalsma H, et al. (1998): OV RG
sipT sipT None Positive 1510552..1510573 None TTTTTTATGATAAAGTAAAAGA Tjalsma H, et al. (1998): OV RG NB
wapA-yxxG wapA SigA Negative 4029620..4029643 -42:-19 AAAAATATTGTAATGATATTTCAG Dartois V, et al. (1998): DB RG DP PE SDM
wapA-yxxG wapA SigA Negative 4029581..4029597 +5:+21 ATATTACTTTTATTACA Dartois V, et al. (1998): DB RG DP PE SDM
yxjJI yxjJ None Negative ND ND ND Dartois V, et al. (1998): Unpublished data




Copyright: Human Genome Center, Inst. Med. Sci., Univ. Tokyo; 1999-2006
Contact: Kenta Nakai