Transcription factor: Hpr

Factor type	Unique (MarR Family)
SWISS-PROT	P11065
SubtiList	BG10659
Consensus seq.	AATANTATT
Comment	One of the transition-state regulators (like Sin) used during the transition state between vegetative growth and the onset of sporulation; transition-state regulators are reviewed in Strauch, M.A. and Hoch, J.A., 1993
Link to	Phylogenetic profile, Weight matrix, Motif alignment & Similar conserved hexameric motifs

Operon	Regulated Gene	Sigma	Regulation	Absolute position	Location	Binding seq.(cis-element)	Experimental evidence
appDFABC	appD	None	Negative	ND	ND	ND	Koide A, et al. (1999): DB OV
aprE	aprE	SigA	Negative	`1105225..1105254`	`-324:-295`	AGTTTATTTTTCAGAATACTTTTATCATCA	Higerd TB, et al. (1972): serine protease activity Ferrari E, et al. (1986): DB RG Henner DJ, et al. (1988): DP RG DB NB PE Henner DJ, et al. (1988): Genetics and biotechnology of Bacilli, vol.2 pp.3-9: DP RG Kallio PT, et al. (1991): GS FT
aprE	aprE	SigA	Negative	`1105197..1105222`	`-292:-267`	CTTTGAAAAAATATCACGATAATATC	Higerd TB, et al. (1972): serine protease activity Ferrari E, et al. (1986): DB RG Henner DJ, et al. (1988): DP RG DB NB PE Henner DJ, et al. (1988): Genetics and biotechnology of Bacilli, vol.2 pp.3-9: DP RG Kallio PT, et al. (1991): GS FT
aprE	aprE	SigA	Negative	`1104989..1105009`	`-79:-59`	TGATATACCTAAATAGAGATA	Higerd TB, et al. (1972): serine protease activity Ferrari E, et al. (1986): DB RG Henner DJ, et al. (1988): DP RG DB NB PE Henner DJ, et al. (1988): Genetics and biotechnology of Bacilli, vol.2 pp.3-9: DP RG Kallio PT, et al. (1991): GS FT
aprE	aprE	SigA	Negative	`1104944..1104965`	`-35:-14`	TACTAAAATATTATTCCATCTA	Higerd TB, et al. (1972): serine protease activity Ferrari E, et al. (1986): DB RG Henner DJ, et al. (1988): DP RG DB NB PE Henner DJ, et al. (1988): Genetics and biotechnology of Bacilli, vol.2 pp.3-9: DP RG Kallio PT, et al. (1991): GS FT
epr	epr	SigD	Negative	`3938530..3938558`	`-332:-304`	AGACAGACCCGATAATAATCAGCGGCATG	Kodgire P, et al. (2006): DP RG GS DB SDM
ispA	ispA	SigA?	Negative	ND	ND	ND	Ruppen ME, et al. (1988): DB RG
nprE	nprE	None	Negative	`1541024..1541049`	`-107:-82`	CTTGATATTATTCAACAAAAACAAAC	Higerd TB, et al. (1972): neutral protease activity Kallio PT, et al. (1991): GS FT
nprE	nprE	None	Negative	`1540946..1540968`	`-26:-4`	GAATGCTAGTTTAATATAACAAT	Higerd TB, et al. (1972): neutral protease activity Kallio PT, et al. (1991): GS FT
oppABCDF	oppA	None	Negative	ND	ND	ND	Koide A, et al. (1999): DB OV
sinIR	sinI	SigA	Negative	`2551470..2551499`	`-86:-57`	ATCTGCAAAATAATATTTCAAGCTAACTTT	Kallio PT, et al. (1991): FT Shafikhani SH, et al. (2002): FT RG
sinIR	sinI	SigA	Negative	`2551544..2551569`	`-10:+14`	TATAATAAAGGTATATTGGAAAAAAA	Kallio PT, et al. (1991): FT Shafikhani SH, et al. (2002): FT RG
yclF	yclF	SigA?	Positive	`417337..417365`	None	AATGAGTATAAATTATATTGACACAAGTA	Caldwell R, et al. (2001): AR HM
yclF	yclF	SigA	Positive	`417309..417337`	None	ATTATATAAGAATATGATTTTTATAATAC	Caldwell R, et al. (2001): AR HM