Transcription factor: AhrC

Factor type ArgR (Unique)
SWISS-PROT P17893
SubtiList BG10309
Consensus seq. CATGAATAAAAATg/tCAAg/t (compiled consensus)
Comment novel mode of DNA recognition; represses the arginine biosynthesis genes and activates the arginine catabolism genes; positive role of AhrC may involve protein-protein interaction with RocR.
Link to Phylogenetic profile, Weight matrix, Motif alignment & Similar conserved hexameric motifs

Operon Regulated Gene Sigma Regulation Absolute position Location Binding seq.(cis-element) Experimental evidence
argCJBD-carAB-argF argC SigA Negative 1194245..1194262 -61:-44 AATGAATAAAAATATTAA Czaplewski LG, et al. (1992): GS FT
Smith MC, et al. (1986): Mung-bean nuclease mapping
argCJBD-carAB-argF argC SigA Negative 1194274..1194290 -31:-14 AATTAATTTTTATTCAT Czaplewski LG, et al. (1992): GS FT
Smith MC, et al. (1986): Mung-bean nuclease mapping
argCJBD-carAB-argF argC SigA Negative 1194421..1194438 +116:+133 ATGCATACTTTATTCATC Czaplewski LG, et al. (1992): GS FT
Smith MC, et al. (1986): Mung-bean nuclease mapping
rocABC rocA SigL Positive 3879572..3879590 -18:+1 CTTGCATTTTTATTCATAT Klingel U, et al. (1995): GS FT
rocDEF rocD SigL Positive 4144577..4144595 -18:+1 CTTGCATTTATATAAAGGG Miller CM, et al. (1997): GS FT




Copyright: Human Genome Center, Inst. Med. Sci., Univ. Tokyo; 1999-2006
Contact: Kenta Nakai