Factor type | LysR |
---|---|
SWISS-PROT | P20668 |
SubtiList | BG10810 |
Consensus seq. | ATCTCANNNTGAGAT, ATCTAANNNATATAT |
Comment | Like many members of LysR family, GltC is encoded just upstream of and in the opposite orientation to its target genes (gltAB); it negatively autoregulates itself. The binding site for the autoregulation is the same with the box I of gltA (-71:-57) in its genome position. Box II of gltA overlaps with its -35 region. cf. GltR |
Link to | Phylogenetic profile, Weight matrix, Motif alignment & Similar conserved hexameric motifs |
Operon | Regulated Gene | Sigma | Regulation | Absolute position | Location | Binding seq.(cis-element) | Experimental evidence |
---|---|---|---|---|---|---|---|
gltAB | gltA | SigA | Positive | 2013879..2013988 | -90:+20 | GTTTGTCTCACATCCATCTATCTCATTTTGAGATTCTTTTGATCTAAATTATATATTGTTTATATCGTTTTGAAAACCTACAATGATTATAGAGTTGTTAGATTTTATGA |
Belitsky BR, et al. (1995): SDM DP Piccossi S, et al. (2007): FP Commichau FM, et al. (2007): RG, in vivo protein interaction assay Bohannon DE, et al. (1989): S1 |
gltC | gltC | SigA | Negative | 2013955..2013969 | +5:+19 | ATCTCAAAATGAGAT |
Belitsky BR, et al. (1995): SDM DP Bohannon DE, et al. (1989): S1 |
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