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Copyright: Human Genome Center, Inst. Med. Sci., Univ. Tokyo; 1999-2008
Contact: Kenta Nakai |
| Regulated Operon: | aprE |
| Genes | Synonyms | Direction | Genome position | Function | COG ID | Conserved groups |
|---|---|---|---|---|---|---|
| aprE | sprE | - | 1104423..1105568 | COG1404O |
| Operon evidence: | Northern blotting; upstream and downstream genes are on the opposite strand |
|---|---|
| Reference: | Genbank Y14083, Ferrari E, et al.: Genetics and biotechnology of Bacilli, vol.2 pp.39-44 (1988) |
| Comments: |
| Binding factor |
Regulation | Location | Absolute position | Binding seq.(cis-element) | Experimental evidence |
|---|---|---|---|---|---|
| AbrB | Negative | -59:+18 | 1105609..1105685 | AAAATCATCTCAAAAAAATGGGTCTACTAAAATATTATTCCATCTATTACAATAAATTCACAGAATAGTCTTTTAAG |
Ferrari E, et al. (1986): DB RG Ferrari E, et al. (1988): Genetics and biotechnology of Bacilli, vol.2 pp.39-44: DP NB Strauch MA, et al. (1989): GS FT Ogura M, et al. (2003): DB RG |
| DegU | Positive | -83:-24 | 1105645..1105704 | GATATACCTAAATAGAGATAAAATCATCTCAAAAAAATGGGTCTACTAAAATATTATTCC |
Kunst F, et al. (1974): serine protease activity; DB Ayusawa D, et al. (1975): protease activity; DB Yoneda Y & Maruo B (1975): serine protease activity; DB Lepesant JA, et al. (1976): Microbiology-1976, edited by David Schlessinger; pages 58-69: DB, serine protease activity Ferrari E, et al. (1986): DB RG Tanaka T & Kawata M (1988): serine protease activity; DB Henner DJ, et al. (1988): Genetics and biotechnology of Bacilli, vol.2 pp.3-9: DP RG Mukai K, et al. (1992): DP DB OV RG Ogura M, et al. (2003): RG DB GS Shimane K & Ogura M (2004): SDM DB RG Kobayashi K, et al. (2010): AR HB DB GS |
| Hpr | Negative | -324:-295 | 1105921..1105950 | AGTTTATTTTTCAGAATACTTTTATCATCA |
Higerd TB, et al. (1972): serine protease activity Ferrari E, et al. (1986): DB RG Henner DJ, et al. (1988): DP RG DB NB PE Henner DJ, et al. (1988): Genetics and biotechnology of Bacilli, vol.2 pp.3-9: DP RG Kallio PT, et al. (1991): GS FT Abe S. et al. (2009): Disruption of glnA, glutamine synthetase gene |
| Hpr | Negative | -292:-267 | 1105893..1105918 | CTTTGAAAAAATATCACGATAATATC |
Higerd TB, et al. (1972): serine protease activity Ferrari E, et al. (1986): DB RG Henner DJ, et al. (1988): DP RG DB NB PE Henner DJ, et al. (1988): Genetics and biotechnology of Bacilli, vol.2 pp.3-9: DP RG Kallio PT, et al. (1991): GS FT |
| Hpr | Negative | -79:-59 | 1105685..1105705 | TGATATACCTAAATAGAGATA |
Higerd TB, et al. (1972): serine protease activity Ferrari E, et al. (1986): DB RG Henner DJ, et al. (1988): DP RG DB NB PE Henner DJ, et al. (1988): Genetics and biotechnology of Bacilli, vol.2 pp.3-9: DP RG Kallio PT, et al. (1991): GS FT |
| Hpr | Negative | -35:-14 | 1105640..1105661 | TACTAAAATATTATTCCATCTA |
Higerd TB, et al. (1972): serine protease activity Ferrari E, et al. (1986): DB RG Henner DJ, et al. (1988): DP RG DB NB PE Henner DJ, et al. (1988): Genetics and biotechnology of Bacilli, vol.2 pp.3-9: DP RG Kallio PT, et al. (1991): GS FT Abe S. et al. (2009): Disruption of glnA, glutamine synthetase gene |
| SigA | Promoter | -59:+18 | 1105609..1105685 | AAAATCATCTCAAAAAAATGGGTCTACTAAAATATTATTCCATCTATTACAATAAATTCACAGAATAGTCTTTTAAG |
Henner DJ, et al. (1988): PE NB DP Ferrari E, et al. (1988): RG PE DP NB Park SS, et al. (1989): DP S1, in-vitro transcription assay |
| SinR | Negative | -265:-220 | 1105846..1105891 | ATTGTTCTCACGGAAGCACACGCAGGTCATTTGAACGAATTTTTTC |
Gaur NK, et al. (1991): DP GS FT Olmos J, et al. (1997): DB RG Ogura M, et al. (2003): DB RG |
| TenA | Positive | ND | ND | ND |
Pang AS, et al. (1991): DB |
| Terminator sequence | Absolute position | Position from stop codon | Free energy [kcal/mol] |
Downstream of |
|---|---|---|---|---|
| AAAAAGAAGCAGGTTCCTCCATACCTGCTTCTTTTTATTTGTCAGC >>>>>>>>> <<<<<<<<< |
aprE |
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