 |
Copyright: Human Genome Center, Inst. Med. Sci., Univ. Tokyo; 1999-2006
Contact: Kenta Nakai |
| Regulated Operon: | citZ-icd-mdh |
| Genes | Synonyms | Direction | Genome position | Function | COG ID | Genus clusters |
|---|---|---|---|---|---|---|
| citZ | citA2 | - | 2980190..2981308 | citrate synthase II | COG0372 | citZ-BAC citZ-STA |
| icd | citC | - | 2978755..2980026 | isocitrate dehydrogenase | COG0538 | citC-BAC citC-STA citC-BAC citC-STA |
| mdh | citH | - | 2977773..2978711 | malate dehydrogenase | COG0039 | mdh-BAC-1 mdh-BAC-2 citM-BAC mdh-BAC-2 |
| Operon evidence: | Genome analysis |
|---|---|
| Reference: | Jin S & Sonenshein AL (1994), Jin S, et al. (1996), Lapidus A, et al. (1997), Genbank AF008220 |
| Comments: | internal promoters in front of icd and mdh |
| Binding factor |
Regulation | Location | Absolute position | Binding seq.(cis-element) | Experimental evidence |
|---|---|---|---|---|---|
| CcpA | Negative | +80:+97 | 2981406..2981423 | AATGTAAGCATTTTCTTT |
Kim HJ, et al. (2002): PE DB RG SDM GS |
| CcpC | Negative | -11:+5 | 2981498..2981513 | ATAATGAGAATAGGCT |
Jourlin-Castelli C, et al. (2000): RG GS FT Kim HJ, et al. (2002): PE DB RG SDM FT |
| CcpC | Negative | +21:+44 | 2981459..2981482 | TTATAAAAATTTGTTATGTTCTTT |
Jourlin-Castelli C, et al. (2000): RG GS FT Kim HJ, et al. (2002): PE DB RG SDM FT |
| SigA | Promoter | -48:+18 | 2981485..2981550 | TATAGGTAAACATTTAACAAATGTCTGATTATTGTTTATAATGAGAATAGGCTTAAACTTAAATAA |
Jin S, et al. (1994): PE |
| SigA | Promoter | -45:+18 | 2980091..2980153 | GCCTCTTGTTCAGACATCAAAATTGGGTTACACTTTAAATTGAATGTTAGGAAAAATCATTTT |
Jin S, et al. (1994): PE |
| Terminator sequence | Absolute position | Position from stop codon | Free energy [kcal/mol] |
Downstream of |
|---|---|---|---|---|
| AGAAAGGCTTGCTTAATACAGCCTTTCTCTTTTTACTA >>>> <<<< |
mdh |
|