Regulated Operon: ureABC

Genes
Genes Synonyms Direction Genome position Function COG ID Genus clusters
ureA
- 3767813..3768130 urease (gamma subunit) COG0831 ureA-STA  
ureB
- 3767442..3767816 urease (beta subunit) COG0832 ureB-STA  
ureC
- 3765736..3767445 urease (alpha subunit) COG0804  

Operon evidence: Northern blotting (2.6 kb transcript)
Reference: Cruz Ramos H, et al. (1997), Yoshida K, et al. (2003)
Comments:


Promoters

Binding
factor
Regulation Location Absolute position Binding seq.(cis-element) Experimental evidence
CodY Negative ND ND ND Debarbouille M, et al. (1997): DP DB
GlnR Negative +7:+23 3768947..3768963 TGTAAACTTTTATAACA Wray LV Jr, et al. (1997): DB DP PE
GlnR Negative -99:-83 3769052..3769068 TGTGAATAAATATAACA Wray LV Jr, et al. (1997): DB DP PE
PucR Positive -78:-54 3769023..3769047 AAGAAGCTGATTTGGTCAAGGTAAC Brandenburg JL, et al. (2002): RG
SigA Promoter -38:+8 3768962..3769007 TTCTTTGAATTAATAGGCCTCTTCTATATAATGATGACATAAGTTG Wray LV Jr, et al. (1997): PE RG
SigH Promoter -44:+4 3768397..3768444 AACAATTGGAAGGAATTCAGATTTTAATTGTCGAACTAGTCAGACAAG Wray LV Jr, et al. (1997): PE RG

Terminator

Terminator sequence Absolute position Position from stop codon Free energy
[kcal/mol]
Downstream of
AGACGCGGCCGGAGTGCATCCGGCCGTTCTATTGACTAAAA
     >>>>>>>>     <<<<<<<<
3765708..3765728
8..28
-18.3
ureC

Overview



Upper Region






Copyright: Human Genome Center, Inst. Med. Sci., Univ. Tokyo; 1999-2006
Contact: Kenta Nakai