Transcription factor: MtrB

Factor type TRAP
SWISS-PROT P19466
SubtiList BG10278
Consensus seq. (G/U)AG repeats
Comment tryptophan operon RNA-binding attenuation protein (TRAP). Regulation of tryptophan biosynthesis (required for transcription and translation) attenuation
Link to Phylogenetic profile

Operon Regulated Gene Sigma Regulation Absolute position Location Binding seq.(cis-element) Experimental evidence
pabBAC-sul-folBK-yazB-yacF-lysS pabA SigA Negative 84233..84284 None GAGCATTAGAGCTGAGCGAAGAAGAGACAAAAATTAGATGAGGTGAGCGGAG Kane JF (1977): DB, anthranilate synthase activity, tryptophan excretion measurement
Babitzke P, et al. (1994): filter binding assay
Yang M, et al. (1995): RG DP SDM
Lee AI, et al. (1996): DB RG
Du H, et al. (1997): FT, in-vitro translation
Valbuzzi A & Yanofsky C (2001): DB RG
Yakhnin H, et al. (2004): RG DB GS
trpEDCFBA-hisC-tyrA-aroE trpE SigA Negative 2376728..2376783 None TAGAATGAGTTGAGTTAGAGAATAGGGTAGCAGAGAATGAGTTTAGTTGAGCTGAG Steinberg W (1974): anthranilate and tryptophan synthase measurement
Kane JF (1977): DB, tryptophan excretion measurement
Shimotsu H & Henner DJ (1984): DP
Shimotsu H, et al. (1986): NB DP SDM RG
Kuroda MI, et al. (1988): DP RG
Gollnick P, et al. (1990): DB RG OV
Babitzke P, et al. (1992): RG OV
Otridge J & Gollnick P (1993): RO NB GS
Babitzke P & Yanofsky C (1993): RO NB OV GS DP
Babitzke P, et al. (1994): filter binding assay, FT
Antson AA, et al. (1995): DP RG SDM
Merino E, et al. (1995): RG SDM DP
Lee AI, et al. (1996): DB RG DP
Yang M, et al. (1997): RG GS DB
Du H & Babitzke P (1998): RG DB, in-vitro translation, ribosome toeprint, RNA structure mapping
Sudershana S, et al. (1999): DP RG SDM DB GS OV NB, in-vitro transcription
Du H, et al. (2000): GS FT RG DP
Valbuzzi A & Yanofsky C (2001): DB RG
Yakhnin AV & Babitzke P (2002): RO
rtpA-ycbK ycbK SigA Negative 277307..277365 None AAGTAAAGGAGAAAAGCTGAGCTGAGATGAGAGCAGAAGAGCAGAGTAAGATTCGTGAG Sarsero JP, et al. (2000): RG DB DP
Yakhnin H, et al. (2006): RG GS FT, toeprint
yhaG yhaG SigA Negative 1074448..1074522 None AATGATGAGCATATTATTGGAGGGCAAAAAGCTTAGCAGAGGAGAGCATAGTTATGAAAACAAAAGAGTTAGTCA Sarsero JP, et al. (2000): DB RG, RNA dot blot analysis
Yakhnin H, et al. (2004): RG DB GS FT




Copyright: Human Genome Center, Inst. Med. Sci., Univ. Tokyo; 1999-2006
Contact: Kenta Nakai