Regulated Operon: aprE

Genes
Genes Synonyms Direction Genome position Function COG ID Conserved groups
aprE sprE - 1104423..1105568
COG1404O  

Operon evidence: Northern blotting; upstream and downstream genes are on the opposite strand
Reference: Genbank Y14083, Ferrari E, et al.: Genetics and biotechnology of Bacilli, vol.2 pp.39-44 (1988)
Comments:


Promoters

Binding
factor
Regulation Location Absolute position Binding seq.(cis-element) Experimental evidence
AbrB Negative -59:+18 1105609..1105685 AAAATCATCTCAAAAAAATGGGTCTACTAAAATATTATTCCATCTATTACAATAAATTCACAGAATAGTCTTTTAAG Ferrari E, et al. (1986): DB RG
Ferrari E, et al. (1988): Genetics and biotechnology of Bacilli, vol.2 pp.39-44: DP NB
Strauch MA, et al. (1989): GS FT
Ogura M, et al. (2003): DB RG
DegU Positive -83:-24 1105645..1105704 GATATACCTAAATAGAGATAAAATCATCTCAAAAAAATGGGTCTACTAAAATATTATTCC Kunst F, et al. (1974): serine protease activity; DB
Ayusawa D, et al. (1975): protease activity; DB
Yoneda Y & Maruo B (1975): serine protease activity; DB
Lepesant JA, et al. (1976): Microbiology-1976, edited by David Schlessinger; pages 58-69: DB, serine protease activity
Ferrari E, et al. (1986): DB RG
Tanaka T & Kawata M (1988): serine protease activity; DB
Henner DJ, et al. (1988): Genetics and biotechnology of Bacilli, vol.2 pp.3-9: DP RG
Mukai K, et al. (1992): DP DB OV RG
Ogura M, et al. (2003): RG DB GS
Shimane K & Ogura M (2004): SDM DB RG
Kobayashi K, et al. (2010): AR HB DB GS
Hpr Negative -324:-295 1105921..1105950 AGTTTATTTTTCAGAATACTTTTATCATCA Higerd TB, et al. (1972): serine protease activity
Ferrari E, et al. (1986): DB RG
Henner DJ, et al. (1988): DP RG DB NB PE
Henner DJ, et al. (1988): Genetics and biotechnology of Bacilli, vol.2 pp.3-9: DP RG
Kallio PT, et al. (1991): GS FT
Abe S. et al. (2009): Disruption of glnA, glutamine synthetase gene
Hpr Negative -292:-267 1105893..1105918 CTTTGAAAAAATATCACGATAATATC Higerd TB, et al. (1972): serine protease activity
Ferrari E, et al. (1986): DB RG
Henner DJ, et al. (1988): DP RG DB NB PE
Henner DJ, et al. (1988): Genetics and biotechnology of Bacilli, vol.2 pp.3-9: DP RG
Kallio PT, et al. (1991): GS FT
Hpr Negative -79:-59 1105685..1105705 TGATATACCTAAATAGAGATA Higerd TB, et al. (1972): serine protease activity
Ferrari E, et al. (1986): DB RG
Henner DJ, et al. (1988): DP RG DB NB PE
Henner DJ, et al. (1988): Genetics and biotechnology of Bacilli, vol.2 pp.3-9: DP RG
Kallio PT, et al. (1991): GS FT
Hpr Negative -35:-14 1105640..1105661 TACTAAAATATTATTCCATCTA Higerd TB, et al. (1972): serine protease activity
Ferrari E, et al. (1986): DB RG
Henner DJ, et al. (1988): DP RG DB NB PE
Henner DJ, et al. (1988): Genetics and biotechnology of Bacilli, vol.2 pp.3-9: DP RG
Kallio PT, et al. (1991): GS FT
Abe S. et al. (2009): Disruption of glnA, glutamine synthetase gene
SigA Promoter -59:+18 1105609..1105685 AAAATCATCTCAAAAAAATGGGTCTACTAAAATATTATTCCATCTATTACAATAAATTCACAGAATAGTCTTTTAAG Henner DJ, et al. (1988): PE NB DP
Ferrari E, et al. (1988): RG PE DP NB
Park SS, et al. (1989): DP S1, in-vitro transcription assay
SinR Negative -265:-220 1105846..1105891 ATTGTTCTCACGGAAGCACACGCAGGTCATTTGAACGAATTTTTTC Gaur NK, et al. (1991): DP GS FT
Olmos J, et al. (1997): DB RG
Ogura M, et al. (2003): DB RG
TenA Positive ND ND ND Pang AS, et al. (1991): DB

Terminator

Terminator sequence Absolute position Position from stop codon Free energy
[kcal/mol]
Downstream of
AAAAAGAAGCAGGTTCCTCCATACCTGCTTCTTTTTATTTGTCAGC
     >>>>>>>>>        <<<<<<<<<
1104388..1104413
10..35
-15.2
aprE

Overview



Upper Region






Copyright: Human Genome Center, Inst. Med. Sci., Univ. Tokyo; 1999-2008
Contact: Kenta Nakai