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Copyright: Human Genome Center, Inst. Med. Sci., Univ. Tokyo; 1999-2006
Contact: Kenta Nakai |
| Regulated Operon: | comK |
| Genes | Synonyms | Direction | Genome position | Function | COG ID | Genus clusters |
|---|---|---|---|---|---|---|
| comK | + | 1116413..1116991 | competence transcription factor (CTF) | COG4903 | x1066-BAC |
| Operon evidence: | Genome analysis; upstream and downstream gene are on the opposite strand |
|---|---|
| Reference: | Van Sinderen D, et al. (1994) |
| Comments: |
| Binding factor |
Regulation | Location | Absolute position | Binding seq.(cis-element) | Experimental evidence |
|---|---|---|---|---|---|
| AbrB | Negative | -81:+64 | 1116296..1116415 | CATTAAATATCATTAAAAGATGATTTTATCTTAAATGTTAAAAAAACCTGTCGTTTTACAAAAACAGATGATAGATTATTAGTATAAATTTTGCAGAAAAAGGATGGAGGCCATAATATG |
Hamoen LW, et al. (2003): FT Hahn J, et al. (1994): DB |
| CodY | Negative | -77:+13 | 1116300..1116364 | AAATATCATTAAAAGATGATTTTATCTTAAATGTTAAAAAAACCTGTCGTTTTACAAAAACAGAT |
Serror P, et al. (1996): DB FT GS |
| ComK | Positive | -118:-83 | 1116259..1116294 | TGAAAGTAAAATCGGTTTATTACTAGTCATTTAGTA |
Van Sinderen D & Venema G (1994): RG OV DB; Western blot Van Sinderen D, et al. (1995): GS Hamoen LW, et al. (1998): FT Berka RM, et al. (2002): AR HM |
| ComK | Positive | -83:-55 | 1116294..1116322 | ACCATTAAATATCATTAAAAGATGATTTT |
Van Sinderen D & Venema G (1994): RG OV DB; Western blot Van Sinderen D, et al. (1995): GS Hamoen LW, et al. (1998): FT Berka RM, et al. (2002): AR HM |
| DegU | Positive | -102:-73 | 1116275..1116309 | TTATTACTAGTCATTTAGTACCATTAAATATCATT |
Hahn J, et al. (1994): DB Van Sinderen D & Venema G (1994): RG DB; Western blot Ogura M, et al. (1996): DB RG Hamoen LW, et al. (2000): GS FT Shimane K & Ogura M (2004): SDM RG |
| Med | Positive | ND | ND | ND |
Ogura M, et al. (1997): DP |
| Rok | Negative | ND | ND | ND |
Hoa TT, et al. (2002): GS DB RG OV Albano M, et al. (2005): GS |
| SigA | Promoter | -49:+20 | 1116328..1116396 | AAATGTTAAAAAAACCTGTCGTTTTACAAAAACAGATGATAGATTATTAGTATAAATTTTGCAGAAAAA |
Van Sinderen D, et al. (1994): PE |
| Terminator sequence | Absolute position | Position from stop codon | Free energy [kcal/mol] |
Downstream of |
|---|---|---|---|---|
| ATTAGAAAAATAGGAAGGAGCTGACCGAACAGGGCAGCTCCTTTCATAAAGCTATG >>>>>>>>>> <<<<<<<<<< |
comK |
|