Transcription factor: AbrB

Factor type	AbrB-SpoVT
SWISS-PROT	P08874
SubtiList	BG10100
Consensus seq.	WAWWTTTWCAAAAAAW, TGGNA
Comment	Bi-functional; expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation; acts as the Spo0A-AbrB circuit; also involved in catabolite repression.
Link to	Phylogenetic profile, Weight matrix, Motif alignment & Similar conserved hexameric motifs

Operon	Regulated Gene	Sigma	Regulation	Absolute position	Location	Binding seq.(cis-element)	Experimental evidence
abrB	abrB	SigA	Negative	`45219..45248`	`-43:-14; -29:+1`	CAAAATGATTGACGATTATTGGAAACCTTG	Strauch MA, et al. (1989): GS FT
aprE	aprE	SigA	Negative	`1104917..1104989`	`-59:+15`	AAAATCATCTCAAAAAAATGGGTCTACTAAAATATTATTCCATCTATTACAATAAATTCACAGAATAGTCTTT	Ferrari E, et al. (1986): DB RG Ferrari E, et al. (1988): Genetics and biotechnology of Bacilli, vol.2 pp.39-44: DP NB Strauch MA, et al. (1989): GS FT Ogura M, et al. (2003): DB RG
argCJBD-carAB-argF	argC	SigA	Positive	ND	ND	ND	O'Reilly M, et al. (1994): RG
citB	citB	SigA	Positive	`1925786..1925834`	`-35:+14`	TTTACTTATGTATGATTTTGTTTTAATATGAAATTGTGAGAAAATTGTG	Kim HJ, et al. (2003): RG FT
comK	comK	SigA	Negative	`1116296..1116415`	`-81:+64`	CATTAAATATCATTAAAAGATGATTTTATCTTAAATGTTAAAAAAACCTGTCGTTTTACAAAAACAGATGATAGATTATTAGTATAAATTTTGCAGAAAAAGGATGGAGGCCATAATATG	Hamoen LW, et al. (2003): FT Hahn J, et al. (1994): DB
dppABCDE	dppA	SigA	Negative	`1359656..1359689`	`-16:+18`	TTTAATATAATTTGTTAGAATATTCATAATTTAG	Slack FJ, et al. (1991): FT DB
yrhIJ	yrhI	None	Negative	ND	ND	ND	Gustafsson MC, et al. (2001): RG
sdpRI	yvbA	SigA	Negative	ND	ND	ND	Ellermeier CD, et al. (2006): DB RG
ftsAZ	ftsA	None	Negative	`1595633..1595651`	`-1:+18`	AATAAACATAAAATGTGAA	Strauch MA, et al. (1995): FT
ftsAZ	ftsA	None	Negative	`1595667..1595690`	`+34:+57`	TTCTGTTGTTATTTTTTGTTACAC	Strauch MA, et al. (1995): FT
hpr	hpr	None	Positive	ND	ND	ND	Strauch MA, et al. (1989): GS
hut	hutP	SigA	Positive	`4040667..4040689`	`+199:+221`	CAATTGAAACCGCTTCCAAAAAG	Fisher SH, et al. (1994): FT
kinB-kapB	kinB	SigA	Negative	`3229046..3229074`	`-34:-6`	TTTTACTTCTAATATTTAGTGTTATAATA	Strauch MA, et al. (1995): FT
pbpE-racX	pbpE	SigW	Negative	`3534576..3534600`	`-84:-60`	ATGTGATGGGTTAAAAAGGATCTCT	Strauch MA, et al. (1995): FT
pbpE-racX	pbpE	SigW	Negative	`3534543..3534568`	`-52:-27`	GGATTTTTCAAAATATTTGAAACGTT	Strauch MA, et al. (1995): FT
rbsRKDACB	rbsR	SigA	Positive	`3700264..3700340`	`-133:-67`	GAAATCTTCATCCATATTTGTGAAGACTTTGTCAAAAAAAGAGTGAAAACCTTAAATTTTTCAATTATATATACAAT	Strauch MA, et al. (1995): DB FT
rbsRKDACB	rbsR	SigA	Positive	`3700402..3700434`	`-4:+29`	CTATGTAAACGGTTACATAAACAAGGAGGAGCT	Strauch MA, et al. (1995): DB FT
rok	rok	None	Negative	ND	ND	ND	Hoa TT, et al. (2002): RG DB
sboAX-albABCDEFG	sboA	SigA	Negative	ND	ND	ND	Zheng G, et al. (2000): DB
senS	senS	None	Negative	ND	ND	ND	McCready P, et al. (1993): DB RG
sigH	sigH	SigA	Negative	`116537..116576`	`-35:+5`	TGACGCTTTTTTGCCCAATACTGTATAATATTTCTATCTA	Zuber P, et al. (1988): Genetics and biotechnology of Bacilli, vol.2 pp.123-127: DB RG Strauch MA, et al. (1995): FT
sigW-ybbM	sigW	SigW	Negative	`194824..194850`	`+14:+41`	GAGGTTAGATAAATATGGAAATGATGA	Qian Q, et al. (2002): RG FT
sinIR	sinI	SigA	Negative	`2551579..2551601`	`+24:+46`	TTTAATGGCAAATGACTTCCAGA	Strauch MA (1995): GS Shafikhani SH, et al. (2002): PE FT Shafikhani SH & Leighton T (2004): DB RG
spo0E	spo0E	SigA	Negative	`1429903..1429937`	`-39:-5`	TATGTTTACAAATAAAGTATAATCTGTAATAATGC	Strauch MA, et al. (1989): GS FT
spoVG	spoVG	SigH	Negative	`55753..55822`	`-75:-6`	TAACTATATCCTATTTTTTCAAAAAATATTTTAAAAACGAGCAGGATTTCAGAAAAAATCGTGGAATTGA	Zuber P & Losick R (1983): DB DP RG Zuber P & Losick R (1987): DB RG RO Zuber P, et al. (1988): Genetics and biotechnology of Bacilli, vol.2 pp.123-127: DB RG Furbass R, et al. (1991): GS FT
skf	ybcO	SigA	Negative	ND	ND	ND	Fujita M, et al. (2005): RG
ycnK	ycnK	None	Negative	ND	ND	ND	Hamon MA, et al. (2004): AR RT-PCR
yknWXYZ	yknW	SigW	Negative	`1502803..1502848`	`-60:-15`	GGTTTTTGGAAATTTATTAGAAAAACATGAAACTTTTTGATATCCT	Qian Q, et al. (2002): RG FT
yoaW	yoaW	SigE	Negative	ND	ND	ND	Hamon MA, et al. (2004): AR RT-PCR
yocH	yocH	SigA	Negative	ND	ND	ND	Hamon MA, et al. (2004): AR RT-PCR
sdp	yvaW	None	Negative	ND	ND	ND	Fujita M, et al. (2005): RG DB
yvlABCD	yvlA	SigW	Negative	`3607914..3607938`	`-79:-55`	TTAAAATCCAATTTCCGTAAATCGG	Qian Q, et al. (2002): RG FT
yvqH	yvqH	None	Negative	ND	ND	ND	Hamon MA, et al. (2004): AR RT-PCR
yxbBA-yxnB-asnH-yxaM	yxbB	None	Negative	ND	ND	ND	Hamon MA, et al. (2004): AR RT-PCR
yxbCD	yxbC	None	Negative	ND	ND	ND	Hamon MA, et al. (2004): AR RT-PCR
yxzE	yxzE	SigW	Negative	`3981949..3981990`	`-17:+25`	TCATCCGTATAACAGATATGGTGAAAAAAGGGAGTGACGCGA	Qian Q, et al. (2002): RG FT