Transcription factor: ComA

Factor type	LuxR/UhpA family
SWISS-PROT	P14204
SubtiList	BG10381
Consensus seq.	TTGCGGNNNNCCGCAA----------TTGCNNNNATTT
Comment	positive regulator of genes involved in late-growth expression and in response to environmental stress; is phosphorylated by ComP; may cause DNA bending by bridging two binding sites
Link to	Phylogenetic profile, Weight matrix, Motif alignment & Similar conserved hexameric motifs

Operon	Regulated Gene	Sigma	Regulation	Absolute position	Location	Binding seq.(cis-element)	Experimental evidence
degQ	degQ	SigA	Positive	`3256383..3256425`	`-74:-32`	AGATTTGCGGTGTCACGCAGGACTTTTTTGCATACTTTTCGGT	Msadek T, et al. (1991): DP DB RG
pel	pel	None	Positive	`827206..827221`	None	TTGCAGAATGCCGCAA	Comella N & Grossman AD (2005): DB AR OV RG
rapA-phrA	rapA	SigA	Positive	`1315073..1315112`	`-75:-36`	TTGCGGTTAGCCGAAATTCGACAATTGCGGTTATTTTGCG	Mueller JP, et al. (1992): DP RO DB
rapC-phrC	rapC	SigA	Positive	`428295..428373`	`-72:+7`	TTGCGTGCTCCCGAAAACAAAGATTGCGTGTTTTTCGGGTTGGGACGGCCTATAAACATGATAAAATATGACATAAACA	Lazazzera BA, et al. (1999): DP HM PE Bongiorni C, et al. (2005): GS
rapE-phrE	rapE	None	Positive	ND	ND	ND	Jiang M, et al. (2000): RG
rapF-phrF	rapF	None	Positive	ND	ND	ND	Bongiorni C, et al. (2005): RG DB
srfAA-srfAB-comS-srfAC-srfAD	srfAA	SigA	Positive	`376117..376154`	`-118:-81`	TTGCGGCATCCCGCAAAAAATATTGCTGTAAATAAACT	Hahn J & Dubnau D (1991): DB RG Nakano MM, et al. (1991): DP SDM Roggiani M & Dubnau D (1993): GS FT
srfAA-srfAB-comS-srfAC-srfAD	srfAA	SigA	Positive	`376161..376198`	`-74:-37`	TTTCGGCATCCCGCATGAAACTTTTCACCCATTTTTCG	Hahn J & Dubnau D (1991): DB RG Nakano MM, et al. (1991): DP SDM Roggiani M & Dubnau D (1993): GS FT