Transcription factor: PhoP

Factor type	LuxR/UhpA
SWISS-PROT	ND
SubtiList	ND
Consensus seq.	TT(A/T/C)ACA-N3 to N7-TT(A/T/C)ACA
Comment	PhoP is phosphorylated by PhoR sensor kinase. PhoP~P binds to DNA only(?) under phosphate starvation condition. A consensus core PhoP-binding region composed of four TT(A/T)ACA direct repeats each separated by 5+-2 non-conserved nucleotides was identified.
Link to	Phylogenetic profile

Operon	Regulated Gene	Sigma	Regulation	Absolute position	Location	Binding seq.(cis-element)	Experimental evidence
glpTQ	glpQ	SigA	Positive	`233944..233993`	`-65:-16`	GAAAGACACATAAAAGATTAATAGTTTTCCAACACGCCGTTTACATCCGT	Antelmann H, et al. (2000): NB DB 2D-PAGE Allenby NE, et al. (2005): DB AR
phoA	phoA	SigA	Positive	`1018505..1018573`	`-87:-20`	GCGTTTTTTCATTTCCTTACAAGGCTTTACTTATTGTTTACATGATCAACAGCCGCATTTAACAAAGTT	Liu W, et al. (1998): DP GS RO FT Allenby NE, et al. (2005): DB AR NB
phoB-ydhF	phoB	SigA; SigE	Positive (SigA promoter); Negative (SigE promoter)	`621529..621587`	`-65:-7 (SigA); +18:+76 (SigE)`	TCTTGTAAATCCAATCTTTAAAATCGATTAATACTAGCTTAACAGTTTAAAAATATAAT	Liu W, et al. (1997): GS FT Abdel-Fattah WR, et al. (2005): RG; in-vitro transcription assay; FT Allenby NE, et al. (2005): DB AR
phoB-ydhF	phoB	SigE	Negative (SigE promoter)	`621591..621639`	`-35:+14`	CTAAAACTTCTCATAAAAGAATAACCATTATTTAAGGGTGCCAGTTCAT	Abdel-Fattah WR, et al. (2005): RG; in-vitro transcription assay; FT
phoD	phoD	SigA	Positive	`283918..283967`	`-66:-17`	TTCAGCGCTTACAATCAGTTCACACTTCTTCACAGTCGTTTAACAATGAT	Eder S, et al (1999): PE FT Allenby NE, et al. (2005): DB AR
phoPR	phoP	SigA	Positive	`2978727..2978755`	None	TGTCATGAAAGTATTATCCTAATAAAAAG	Paul S, et al. (2004): FT RG
phoPR	phoP	SigA	Positive	`2978619..2978672`	None	ATCATAAACGTCTTTATTTCTTTTAAAAATGATGTAAAAGGCGAATTGTCGGAA	Pragai Z, et al. (2004): FT GS Paul S, et al. (2004): FT RG
phoPR	phoP	SigA	Positive	`2978561..2978600`	None	ATAAAATCATGAAACATGTTAAGATGACATAAAATAGAGA	Pragai Z, et al. (2004): FT GS
phoPR	phoP	SigA	Positive	`2978455..2978483`	None	ATTGTTACTCTTTTACAGTACAATTTGGA	Paul S, et al. (2004): FT RG
pst	pstS	SigA	Positive	`2581674..2581724`	`-66:-15`	CACTGATTTACAAAACCTTAACATTCGGTTCAAACCCTTTTTACATAGAAC	Liu W, et al. (1998): DP GS FT Qi Y, at al. (1997): PE RG Allenby NE, et al. (2005): DB AR
resABCDE	resA	SigA	Positive	`2421381..2421448`	`-72:-6`	ACGCTTTCTAAATTTCACATAACCTTCAAAAAGTAAGAAATGTGAAATGAACGTGCAATGATATAATT	Birkey SM, et al. (1998): GS FT
resABCDE	resD	SigA	Negative	`2417903..2417972`	`-45:+25`	CGACACAGTTCTCAAACTTTCTCACGATTTGATAAAATGAAAGTAACAGAAGGAAAGCAGGGGGAAAACA	Birkey SM, et al. (1998): GS FT
skf	ybcO	SigA	Positive	ND	ND	ND	Allenby NEE, et al. (2006): DB RG NB GS
tagAB	tagA	SigA	Negative	`3681225..3681310`	`-70:+16`	GGAAACATATTTAAATTTAATGTAAAGATAATGTTAATCCTTTGTTGAAGATTTATGTTAAAATATAAGGTAGCTTGATTTTGCTT	Liu W, et al. (1998): DB FT
tagAB	tagA	SigA	Negative	`3681322..3681351`	`+28:+57`	CGGTTTTTAACTATATAAATAGAATCTTAA	Liu W, et al. (1998): DB FT
tagAB	tagA	SigA	Negative	`3681375..3681415`	`+79:+115`	AACAGAGACTATTCACAATATTCCTTATGTTAACAGTAACT	Liu W, et al. (1998): DB FT
tagDEF	tagD	SigA	Negative	`3681114..3681174`	`-81:-12`	GTCTGAGTGTAATTACATATTTTGGAATGTTTTTCTCCTCATGAGTACTTAACCTTTTTTA	Liu W, et al. (1998): DB FT
tagDEF	tagD	SigA	Negative	`3680924..3680970`	`+122:+168`	ATGAAAAAAGTTATCACATATGGAACTTTTGATTTACTGCATTGGGG	Liu W, et al. (1998): DB FT
tagDEF	tagD	SigA	Negative	`3680986..3681013`	`+79:+106`	TGTTTTTAATAGTGTTTAACATTAGGAA	Liu W, et al. (1998): DB FT
tuaABCDEFGH	tuaA	SigA	Positive	`3658953..3658997`	`-62:-18`	ATTCACACTTCTTAACATACCATTTACATCCAATTAACATCCGTC	Liu W, et al. (1998): DB GS FT Soldo B, et al. (1999): PE RG Allenby NE, et al. (2005): DB AR
vpr	vpr	None	Positive	ND	ND	ND	Allenby NE, et al. (2005): DB AR NB
yfkN	yfkN	None	Positive	`859541..859567`	None	AATAGTTACAAAATATTCTTACAATAG	Allenby NE, et al. (2005): DB RG AR NB
yhbH	yhbH	SigE	Positive	ND	ND	ND	Pragai Z, et al. (2002): RG DB
yjdB	yjdB	None	Positive	`1270144..1270167`	None	ATTATTAACATTTATTTACAAGGA	Allenby NE, et al. (2005): DB AR NB
ykzB-ykoL	ykoL	SigA	Positive	`1398081..1398140`	`-72:-13`	AAAATCTTCGTAAACATAAATTCTTTACATTAGATTCATACCACGTTCATTTAAAAAGAG	Robichon D, et al. (2000): RG PE Pragai Z, et al. (2004): FT GS Abdel-Fattah WR, et al. (2005): RO
yttP	yttP	None	Positive	ND	ND	ND	Pragai Z, et al. (2002): DB
yurI	yurI	None	Positive	ND	ND	ND	Allenby NE, et al. (2005): DB AR RG NB