Transcription factor: Spo0A

Factor type	LuxR/UhpA
SWISS-PROT	P06534
SubtiList	BG10765
Consensus seq.	TGTCGAA
Comment	a key bi-functional regulator to control developmental transcription activities. Increases its affinity after phosphorylation (phosphorelay system). Spo0F is required for the phosphorylation. Two-domain structure. Binding consensus is called 0A box and can be located downstream of the initiation site. Often, two adjacent boxes are found. These listed sites might be viewed in its complementary strand.
Link to	Phylogenetic profile, Weight matrix, Motif alignment & Similar conserved hexameric motifs

Operon	Regulated Gene	Sigma	Regulation	Absolute position	Location	Binding seq.(cis-element)	Experimental evidence
abrB	abrB	SigA	Negative	`45172..45199`	`+7:+34`	ATTTTGTCGAATAATGACGAAGAAAAAT	Perego M & Hoch J (1988): Genetics and Biotechnology of Bacilli, Vol. 2, pp. 129-134: RG DB Strauch M, et al. (1990): FT Fujita M, et al. (2005): RG GS
dltABCDE	dltA	SigX	Positive	`3951092..3951112`	`+1:+21`	ATGTGATTGTCGAAAAAACGG	Perego M, et al. (1995): DB FT
cdd-era	era	None	Positive	ND	ND	ND	Minkovsky N, et al. (2002): DB RG
kinA	kinA	SigH	Negative	`1469285..1469305`	`+13:+33`	ATCTGTATATGTCGAAACACG	Fujita M, et al. (1998): GS
kinC	kinC	SigA	Positive	`1517584..1517613`	`-30:-1`	ATTATTTGTCGAAGAATGGTACAATAAGTA	Kobayashi K, et al. (1995): GS FT
sinIR	sinI	SigA	Positive	`2551503..2551530`	`-50:-26`	ACCATTCGACATCATTCTCGTTTTTTTT	Shafikhani SH, et al. (2002): PE FT
spo0A	spo0A	SigH	Positive	`2518110..2518123`	`-14:+1`	TTTGTCGAATGTAA	Strauch MA, et al. (1992): FT
spo0A	spo0A	SigA	Negative	`2518187..2518221`	`+38:+72`	AATTTCATTTTTAGTCGAAAAACAGAGAAAAACAT	Strauch MA, et al. (1992): FT
spo0A	spo0A	SigA	Negative	`2518239..2518263`	`-15:+20`	AAAAGAAGATTTTTCGACAAATTCA	Strauch MA, et al. (1992): FT
spo0F	spo0F	SigH	Positive	`3809035..3809072`	`-84:-51`	CAAAAGAGAAAATGCTCAGAAAATGTCGTAAAGTAGAC	Strauch MA, et al. (1993): DP SDM FT
spo0F	spo0F	SigH	Positive	`3808936..3808978`	`+11:+53`	TTTGACGAAAATCATAATATTGGGGTGTAAAATGATGAATGAA	Strauch MA, et al. (1993): DP SDM FT
dacF-spoIIAAB-sigF	spoIIAA	SigH	Positive	`2444227..2444242`	`-28:-13`	TCATTCCGTCGAAATC	Baldus JM, et al. (1994): FT Fujita M, et al. (2005): OV RG GS
dacF-spoIIAAB-sigF	spoIIAA	SigH	Positive	`2444247..2444265`	`-51:-33`	TAGTTTTGTCACGGTGAAG	Baldus JM, et al. (1994): FT Fujita M, et al. (2005): OV RG GS
dacF-spoIIAAB-sigF	spoIIAA	SigH	Positive	`2444266..2444285`	`-71:-52`	TAATTATGCCGAATGACCAC	Baldus JM, et al. (1994): FT Fujita M, et al. (2005): OV RG GS
dacF-spoIIAAB-sigF	spoIIAA	SigH	Positive	`2444280..2444311`	`-66:-97`	CGATGGGAGACTGGACAAAATTTAAGTAATTA	Baldus JM, et al. (1994): FT Fujita M, et al. (2005): OV RG GS
spoIIE	spoIIE	SigA	Positive	`70373..70399`	`-134:-108`	TTTTCATTTTTAGACAACATTCCGGAA	York K, et al. (1992): SDM FT Fujita M, et al. (2005): GS
spoIIE	spoIIE	SigA	Positive	`70404..70420`	`-103:-87`	TTTTCATAAACGAATAT	York K, et al. (1992): SDM FT Fujita M, et al. (2005): GS
spoIIE	spoIIE	SigA	Positive	`70425..70441`	`-82:-66`	GCAGAAACCGTCGAAGA	York K, et al. (1992): SDM FT Fujita M, et al. (2005): GS
spoIIE	spoIIE	SigA	Positive	`70459..70479`	`-48:-28`	CCTTCTTTTGACAAAATCCTA	York K, et al. (1992): SDM FT Fujita M, et al. (2005): GS
spoIIGA-sigE-sigG	spoIIGA	SigA	Positive	`1602931..1602945`	`-100:-86`	ATACTTCCTCGACAA	Baldus JM, et al. (1994): SDM RO FT Fujita M, et al. (2005): RG OV GS
spoIIGA-sigE-sigG	spoIIGA	SigA	Positive	`1602946..1602961`	`-85:-70`	ATTAAGCAGATTTCCC	Baldus JM, et al. (1994): SDM RO FT Fujita M, et al. (2005): RG OV GS
spoIIGA-sigE-sigG	spoIIGA	SigA	Positive	`1602976..1602993`	`-55:-38`	TTCCTCTCAACATTAATT	Baldus JM, et al. (1994): SDM RO FT Fujita M, et al. (2005): RG OV GS
spoIIGA-sigE-sigG	spoIIGA	SigA	Positive	`1602990..1603007`	`-41:-24`	AATTGACAGACTTTCCCA	Baldus JM, et al. (1994): SDM RO FT Fujita M, et al. (2005): RG OV GS
skf	ybcO	SigA	Positive	`213809..213876`	`-64:+4`	AATTTTTAGGATAATATACAAAATCCCCCTTACTTCGACAATTGCAATCTGGTATTATCGTATCGCAT	Fujita M, et al. (2005): RG OV, gfp fusion, GS Chen G, et al. (2006): FT, binding site mutation
yqxM-sipW-tasA	yqxM	SigH	Positive	ND	ND	ND	Stover AG & Driks A (1999): Western blot Stover AG & Driks A (1999): RG
yuxH	yuxH	SigA	Negative	`3258327..3258392`	`-49:+17`	TTTTCATGTTTAGACAATTTTCGTCAAATTATTTGATATACTTAGGGGTGAAAGCCGCGCGTATTG	Fujita M, et al. (2005): RG Molle V, et al. (2005): ChIP-on-chip, AR GS
sdp	yvaW	None	Negative	ND	ND	ND	Fujita M, et al. (2005): OV RG GS Molle V, et al. (2005): ChIP-on-chip, AR GS
racA	ywkC	SigH	Positive	ND	ND	ND	Ben-Yehuda S, et al. (2003): DB RG Wu LJ & Errington J (2003): DB Western blot