Transcription factor: SigK

Factor type	ND
SWISS-PROT	P12254
SubtiList	BG10459
Consensus seq.	(c/a)AC(c/a)(-35) - 16bp - CATA---TA(-10)
Comment	sigK is formed by a site-specific recombination event which joins the previously separated spoIVCB and spoIIIC genes into a single cistron.
Link to	Phylogenetic profile, Weight matrix & Motif alignment

Operon	Regulated Gene	Absolute position	Location	Binding seq.(cis-element)	Experimental evidence
cgeAB	cgeA	`2148603..2148650`	`-43:+5`	TTCGACTCATACCAAATAACAGCCGGAAGAATATGAATAACGTGAGTT	Roels S, et al. (1995): PE NB DB
cgeCDE	cgeC	`2148494..2148541`	`-43:+5`	CATAGCCTATACCATAAATCGAAGTCGCACATATTGTGAAACAGAGAT	Roels S, et al. (1995): PE NB DB
cotA	cotA	`685033..685080`	`-42:+6`	ATTTTTTGTAACCATCACGTCCTTATTGTCATTAACTATAGTACCAAT	Sandman K, et al. (1988): RG DP S1
cotB	cotB	`3715918..3715964`	`-43:+4`	TTGAATTAGTTCAACAAATAAATGTGACACGTATATATGCAGTATGT	Zheng LB & Losick R (1990): PE
cotC	cotC	`1905216..1905262`	`-41:+6`	AACTGTCCAAGCCGCAAAATCTACTCGCCGTATAATAAAGCGTAGTA	Zheng L, et al. (1992): PE Zheng LB & Losick R (1990): PE RG DP
cotD	cotD	`2333038..2333085`	`-43:+5`	TTGCATCAGAACATGTACCCCTTATTTTTCATAACTTAGTATTGTAAT	Zheng LB & Losick R (1990): S1 RG
cotE	cotE	`1774999..1775046`	`-43:+5`	ATAAAAATGCACACTAGACAAATGCCCAGCATAAGATAACACGAAGAA	Zheng LB & Losick R (1990): PE S1 RG DP Eichenberger P, et al. (2004): GS
cotF	cotF	`4167039..4167083`	`-43:+2`	AACATCATGAACAACATTGAGCGTTGGGCATATGCTGATATGGAA	Cutting S, et al. (1991): PE
cotG	cotG	`3717149..3717193`	`-42:+3`	GAACACTTATACACTTTTTAAAACCGCGCGTACTATGAGGGTAGT	Sacco M, et al. (1995): PE RG
cotH	cotH	`3717181..3717240`	`-44:+16`	CAATTTGAAATCCTCCTTTTAAAAATATGTTAAGGATGAAGATCCTTACTACCCTCATAG	Naclerio G, et al. (1996): PE DB
cotM	cotM	`1926049..1926108`	`-50:+10`	CTGTTTTTTTATGCGTTCACCCATTTATAATCCACCGCATATGATGTAAAGCAAGGTTGA	Henriques AO, et al. (1997): PE DB RG Reischl S, et al. (2001): RG HB DB
yozR	yozR	`2123939..2124023`	None	CTTTAGAGCATCTTATATTATATCACGTGAAAGATCTGGTGGGCATATACTATTTTGTCCGTGAAGAAAGGATGTGAAGACAATG	Ferguson CC, et al. (2007): DB RG HM
ydgBA-cotP	ydgB	`602726..602777`	None	CAAGGAACAATTGGGTGCAGCGGCGCATAATGTACTGTACAGAAAGATGGAA	Reischl S, et al. (2001): RG HB DB
cotSA-cotS-ytxO	cotSA	`3161928..3161972`	`-42:+3`	CCCATTCCGCACAAGTTGGTTGTTCAGCCGTATCATGATTCTAAC	Abe A, et al. (1995): NB PE Takamatsu H, et al. (1998): DB NB RG Kuwana R, et al. (2002): SDS-PAGE, RG
cotT	cotT	`1280894..1280949`	`-46:+10`	ATGAATGTACATACACCCAACTTAAGCATCAGGAATATGGTAAAAGGAATAAAAAA	Bourne N, et al. (1991): PE Aronson AI, et al. (1989): S1 NB Eichenberger P, et al. (2004): HM AR
cotVWX	cotV	`1252036..1252083`	`-42:+6`	TTTTATTATTCCGCTCTGCACCCCATTTGCATTATATAGAGTATGGAT	Zhang J, et al. (1994): NB PE DB RO
cotVWX	cotX	`1251191..1251238`	`-43:+5`	TATGACTCAGTCAAAATAAGAGGCTCGCTCATTTAATAACAGTAAAAG	Zhang J, et al. (1994): NB PE DB RO
cotYZ	cotY	`1250540..1250587`	`-44:+4`	GTTCACCCACACCAAGTGGGGCACGGGTACATATGTTGTTAAGGACTA	Zhang J, et al. (1994): NB PE DB RO
cwlC	cwlC	`1873587..1873633`	`-41:+6`	AATCGTACAAGCAGAAGCCGTGTTTTTTCATATCCTGTAATGAGGTG	Kuroda A, et al. (1993): RG DB NB PE
cwlH	cwlH	`2649656..2649709`	`-40:+14`	AAAGGCTGTCCATCTCTCTGTTTTCTGCATTCTTATTAATAGGGAGGGATAGAA	Nugroho FA, et al. (1999): RG PE HM
rnc-smc-ftsY	ftsY	`1669382..1669436`	`-50:+5`	ACTCCAATACTTACGGGAGGAATACAGCTTGTCCTTTGAGGGGGCAAAAGAGAAA	Kakeshita H, et al. (2000): PE
gerE	gerE	`2905008..2905055`	`-42:+6`	TGTAAACGTCACCTCCTGCGCCCTTCTTACATATGATATCTCGACTAT	Cutting S, et al. (1989): PE RG
gerPABCDEF	gerPA	`1150506..1150544`	None	TTTCTCTCACACATATGTGCGTTTGTCATAAGCTATCGT	Behravan J, et al. (2000): OV RG Eichenberger P, et al. (2004): HM
spoIVCB-spoIIIC	spoIVCB	`2652915..2652962`	`-39:+9`	CGGTACAGACACAGACAGCCTCCCGGTCACATACATTTACATATAGGC	Kunkel B, et al. (1988): PE RG Kroos L, et al. (1989): RO, SDS-PAGE
spoVFAB-asd-dapG-dapA	spoVFA	`1744274..1744324`	`-40:+11`	TTTTATATTCACCGGTATTTCCTTTTGATCATAAGATGAAGGGGAGCTTAA	Chen NY, et al. (1993): PE Daniel RA & Errington J (1993): RG PE DB
spoVK	spoVK	`1874144..1874190`	`-42:+5`	GGCGTTTGTCACAATCGGCATCCGCTTGAATATCATATAGAGAGAAC	Foulger D & Errington J (1991): PE RG DP DB
sps	spsA	`3893155..3893198`	`-39:+5`	CCTAGCGCAACTTGAGCATAAGCAACATAAGATAACGATAGTTT	Eichenberger P, et al. (2004): Race-PCR
sspG-yurS	sspG	`3354003..3354045`	`-40:+3`	CGTCCAATCTCTTTACTCTCCTATCGAATATCCTGTCACTATC	Bagyan I, et al. (1998): PE RG DB
tgl	tgl	`3212535..3212593`	`-35:+24`	TAACTTTCATTGCCCAAGCTCTTTGCATATCTTATAAAAAACAAGGGGGGCTAAACATG	Kobayashi K, et al. (1998): HM Eichenberger P, et al. (2004): Race-PCR
yabG	yabG	`51529..51574`	`-42:+4`	TGTTTTGCGCACCACATGGACTGCCGCTACATAGGCTAGAGAAGGA	Takamatsu H, et al. (2000): PE
ycsFGI-kipIAR-ycsK	ycsK	ND	ND	ND	Kuwana R, et al. (2002): SDS-PAGE, RG
yfhP	yfhP	`935567..935604`	None	GTTGTACACTAAGGGCACAGTACGATAATATGTTACAT	Fujita M (1999): in-vitro transcription Yamamoto H, et al. (1999): NB RG
yfhP	yfhP	`935555..935593`	None	AGGGCACAGTACGATAATATGTTACATTAAATAGTAATA	Fujita M (1999): in-vitro transcription Yamamoto H, et al. (1999): NB RG
yfnHGFED	yfnE	`801172..801214`	`-37:+6`	GTGAAAGCAAGCGTTATTATTCCTGCATATAATTCGAAGGAGC	Eichenberger P, et al. (2004): Race-PCR
yfnHGFED	yfnH	`798321..798365`	`-39:+6`	TTGGTCACCAAGGCTGGCTTTCTCTCATATCATTACAGTAGATTT	Eichenberger P, et al. (2004): Race-PCR
yhcOP	yhcO	`989634..989683`	`-39:+11`	AATGACACACTGCGAACTCAGGCTGCATAGAGTAAAAATAAAAAGGTACA	Eichenberger P, et al. (2004): Race-PCR
yhjR	yhjR	`1136154..1136208`	`-37:+18`	CTCCGCACATCTCTCCCTGCCCAACATATACTTTTACAGAAGCCCAATTCCTAAG	Eichenberger P, et al. (2004): Race-PCR
yitBA-yisZ	yitB	`1172506..1172550`	`-38:+7`	ACCTGAACCTTTATGCAAAAAATGAATAGTCTGCCTATAACTCGA	Eichenberger P, et al. (2004): Race-PCR
yitCD	yitC	`1172580..1172632`	`-40:+13`	TGCGGAACCATTAAGAGCCCGGCTGAATATGCTTTTTAGCAAAATGGTTTTAT	Eichenberger P, et al. (2004): Race-PCR
yjcB-yjcZ-spoVIF	yjcB	`1252756..1252812`	`-45:+12`	TTTTTGTTTTTTTAACGAGGCGGTCTCGCTCAGCATATATCATAAGCGGGGGGATAA	Kuwana R, et al. (2003): NB DB PE
yjcB-yjcZ-spoVIF	yjcZ	`1253038..1253091`	`-43:+11`	TGCGAATATCCAAGCCGATCCCAGCAGCTCACATAGTGTATAGAGAGTAAAGGA	Kuwana R, et al. (2003): NB DB PE
yjcB-yjcZ-spoVIF	yjcC	`1253314..1253369`	`-45:+11`	ATGTTGGAAAAGCACATTGTATTATGTGCATTCATACAATACCGTATTACTCCGCC	Kuwana R, et al. (2003): NB DB PE
ykuD	ykuD	`1477010..1477070`	`-38:+23`	AATGTAGCAGGATGGGCTCCTCATCAATACTTATAAGTAAAAAAGGAGGATGAGGAAACTG	Eichenberger P, et al. (2004): Race-PCR Kodama T, et al. (2000): NB DB
ykvPQ	ykvP	ND	ND	ND	Kodama T, et al. (2000): NB DB
ylbDE	ylbD	`1567583..1567633`	`-38:+13`	AGGCGAACACAATGCCCGACAAAACGATACATTGTAGTAGGTAACGATTTT	Eichenberger P, et al. (2004): Race-PCR
ymaG	ymaG	ND	ND	ND	Kuwana R, et al. (2002): SDS-PAGE, RG
yndL	yndL	`1915081..1915132`	`-43:+9`	AAAATGAGAAGAACAGCGCCCGGGCTAATGGTATATAATATTGTGAATTTAA	Silvaggi JM, et al. (2006): PE NB DB Eichenberger P, et al. (2004): AR
yngK	yngK	`1959593..1959635`	`-38:+5`	TTAATCACCCTTTTATAGCCCGGGAATACCGTAATAGCGAATA	Eichenberger P, et al. (2004): Race-PCR
yoaN	yoaN	`2038795..2038846`	`-37:+15`	TAGGCACAGCAATCTAAGATTCTGCATAGGCTGAAATAAAATCTTGTTCATT	Costa T, et al. (2004): NB RG HM Eichenberger P, et al. (2004): Race-PCR
yobW	yobW	`2084153..2084204`	`-43:+9`	ATTTCAGCTACTATTTCCGACCGGATAAGCATACACTTCTCAACGGAGGGGA	Henriques AO, et al. (1997): PE HM DB RG
yodHI	yodH	`2133401..2133457`	`-36:+21`	TCATAAACCTATGTCTTTATACGACATATGATAAGGAAAAAGGAGGATTCGATATTG	Eichenberger P, et al. (2004): Race-PCR
ypqA	ypqA	`2337521..2337569`	`-37:+12`	TTTATAACAACATCTGGCATAGACGCATAATCTGGTTAAAAAAGGCGGT	Eichenberger P, et al. (2004): Race-PCR
yqfQ	yqfQ	ND	ND	ND	Kuwana R, et al. (2002): SDS-PAGE, RG
yrkC	yrkC	`2715511..2715561`	`-38:+13`	TTTAGCACACTCCCTTAATAAATGCATAGGATACTATCACAAAAATTTATA	Kuwana R, et al. (2002): SDS-PAGE, RG Eichenberger P, et al. (2004): Race-PCR
ysnD	ysnD	`2897725..2897770`	`-37:+9`	ATAGGCACTTCTCTTGTTCCCTCGGCATACATTAATGATATCTTGC	Eichenberger P, et al. (2004): Race-PCR
ytaA	ytaA	ND	ND	ND	Kuwana R, et al. (2002): SDS-PAGE, RG
ytcC	ytcC	ND	ND	ND	Kuwana R, et al. (2002): SDS-PAGE, RG
ytlABCD	ytlA	`3132286..3132329`	`-36:+8`	GCATTCACACATTTTTATACCCATCATACGATATGTAAAGCAAA	Eichenberger P, et al. (2004): Race-PCR
ywrJ	ywrJ	ND	ND	ND	Kuwana R, et al. (2002): SDS-PAGE, RG
yxeE	yxeE	`4065531..4065579`	`-37:+11`	ATGCCGTGCCACTGTGCCAATGACTACATAAGTTATAAGGAATTCACCC	Eichenberger P, et al. (2004): Race-PCR Takamatsu H, et al. (2000): SDS-PAGE Kuwana R, et al. (2008): DB NB PE