Transcription factor: SigK

Factor type	ND
SWISS-PROT	P12254
SubtiList	BG10459
Consensus seq.	(c/a)AC(c/a)(-35) - 16bp - CATA---TA(-10)
Comment	sigK is formed by a site-specific recombination event which joins the previously separated spoIVCB and spoIIIC genes into a single cistron.
Link to	Phylogenetic profile, Weight matrix, Motif alignment & Similar conserved hexameric motifs

Operon	Regulated Gene	Absolute position	Location	Binding seq.(cis-element)	Experimental evidence
cgeAB	cgeA	`2147801..2147848`	`-43:+5`	TTCGACTCATACCAAATAACAGCCGGAAGAATATGAATAACGTGAGTT	Roels S, et al. (1995): PE NB DB
cgeCDE	cgeC	`2147692..2147739`	`-43:+5`	CATAGCCTATACCATAAATCGAAGTCGCACATATTGTGAAACAGAGAT	Roels S, et al. (1995): PE NB DB
cotA	cotA	`684581..684628`	`-42:+6`	ATTTTTTGTAACCATCACGTCCTTATTGTCATTAACTATAGTACCAAT	Sandman K, et al. (1988): RG DP S1
cotB	cotB	`3714945..3714991`	`-43:+4`	TTGAATTAGTTCAACAAATAAATGTGACACGTATATATGCAGTATGT	Zheng LB & Losick R (1990): PE
cotC	cotC	`1904425..1904471`	`-41:+6`	AACTGTCCAAGCCGCAAAATCTACTCGCCGTATAATAAAGCGTAGTA	Zheng L, et al. (1992): PE Zheng LB & Losick R (1990): PE RG DP
cotD	cotD	`2332235..2332282`	`-43:+5`	TTGCATCAGAACATGTACCCCTTATTTTTCATAACTTAGTATTGTAAT	Zheng LB & Losick R (1990): S1 RG
cotE	cotE	`1774269..1774316`	`-43:+5`	ATAAAAATGCACACTAGACAAATGCCCAGCATAAGATAACACGAAGAA	Zheng LB & Losick R (1990): PE S1 RG DP Eichenberger P, et al. (2004): GS
cotF	cotF	`4166063..4166107`	`-43:+2`	AACATCATGAACAACATTGAGCGTTGGGCATATGCTGATATGGAA	Cutting S, et al. (1991): PE
cotG	cotG	`3716176..3716220`	`-42:+3`	GAACACTTATACACTTTTTAAAACCGCGCGTACTATGAGGGTAGT	Sacco M, et al. (1995): PE RG
cotH	cotH	`3716208..3716267`	`-44:+16`	CAATTTGAAATCCTCCTTTTAAAAATATGTTAAGGATGAAGATCCTTACTACCCTCATAG	Naclerio G, et al. (1996): PE DB
cotM	cotM	`1925265..1925309`	`-42:+3`	TTATGCGTTCACCCATTTATACTCCACCGCATATGATGTAAAGCA	Henriques AO, et al. (1997): PE DB RG Reischl S, et al. (2001): RG HB DB
ydgBA-cotP	ydgB	`602270..602321`	None	CAAGGAACAATTGGGTGCAGCGGCGCATAATGTACTGTACAGAAAGATGGAA	Reischl S, et al. (2001): RG HB DB
cotSA-cotS-ytxO	cotSA	`3160975..3161019`	`-42:+3`	CCCATTCCGCACAAGTTGGTTGTTCAGCCGTATCATGATTCTAAC	Abe A, et al. (1995): NB PE Takamatsu H, et al. (1998): DB NB RG Kuwana R, et al. (2002): SDS-PAGE, RG
cotT	cotT	`1280205..1280260`	`-63:+10`	ATGAATGTACATACACCCAACTTAAGCATCAGGAATATGGTAAAAGGAATAAAAAA	Bourne N, et al. (1991): PE Aronson AI, et al. (1989): S1 NB Eichenberger P, et al. (2004): HM AR
cotVWX	cotV	`1251348..1251395`	`-42:+6`	TTTTATTATTCCGCTCTGCACCCCATTTGCATTATATAGAGTATGGAT	Zhang J, et al. (1994): NB PE DB RO
cotVWX	cotX	`1250503..1250550`	`-43:+5`	TATGACTCAGTCAAAATAAGAGGCTCGCTCATTTAATAACAGTAAAAG	Zhang J, et al. (1994): NB PE DB RO
cotYZ	cotY	`1249852..1249899`	`-44:+4`	GTTCACCCACACCAAGTGGGGCACGGGTACATATGTTGTTAAGGACTA	Zhang J, et al. (1994): NB PE DB RO
cwlC	cwlC	`1872782..1872828`	`-41:+6`	AATCGTACAAGCAGAAGCCGTGTTTTTTCATATCCTGTAATGAGGTG	Kuroda A, et al. (1993): RG DB NB PE
cwlH	cwlH	`2648879..2648932`	`-40:+14`	AAAGGCTGTCCATCTCTCTGTTTTCTGCATTCTTATTAATAGGGAGGGATAGAA	Nugroho FA, et al. (1999): RG PE HM
rnc-smc-ftsY	ftsY	`1668682..1668736`	`-50:+5`	ACTCCAATACTTACGGGAGGAATACAGCTTGTCCTTTGAGGGGGCAAAAGAGAAA	Kakeshita H, et al. (2000): PE
gerE	gerE	`2904075..2904122`	`-42:+6`	TGTAAACGTCACCTCCTGCGCCCTTCTTACATATGATATCTCGACTAT	Cutting S, et al. (1989): PE RG
gerPABCDEF	gerPA	`1149811..1149849`	None	TTTCTCTCACGCATATGTGCGTTTGTCATAAGCTATCGT	Behravan J, et al. (2000): OV RG Eichenberger P, et al. (2004): HM
spoIVCB-spoIIIC	spoIVCB	`2652141..2652188`	`-39:+9`	CGGTACAGACACAGACAGCCTCCCGGTCACATACATTTACATATAGGC	Kunkel B, et al. (1988): PE RG Kroos L, et al. (1989): RO, SDS-PAGE
spoVFAB-asd-dapG-dapA	spoVFA	`1743566..1743616`	`-40:+11`	TTTTATATTCACCGGTATTTCCTTTTGATCATAAGATGAAGGGGAGCTTAA	Chen NY, et al. (1993): PE Daniel RA & Errington J (1993): RG PE DB
spoVK	spoVK	`1873339..1873385`	`-42:+5`	GGCGTTTGTCACAATCGGCATCCGCTTGAATATCATATAGAGAGAAC	Foulger D & Errington J (1991): PE RG DP DB
sps	spsA	`3892172..3892215`	`-39:+5`	CCTAGCGCAACTTGAGCATAAGCAACATAAGATAACGATAGTTT	Eichenberger P, et al. (2004): Race-PCR
sspG-yurS	sspG	`3353030..3353072`	`-40:+3`	CGTCCAATCTCTTTACTCTCCTATCGAATATCCTGTCACTATC	Bagyan I, et al. (1998): PE RG DB
tgl	tgl	`3211574..3211632`	`-35:+24`	TAACTTTCATTGCCCAAGCTCTTTGCATATCTTATAAAAAACAAGGGGGGCTAAACATG	Kobayashi K, et al. (1998): HM Eichenberger P, et al. (2004): Race-PCR
yabG	yabG	`51527..51572`	`-42:+4`	TGTTTTGCGCACCACATGGACTGCCGCTACATAGGCTAGAGAAGGA	Takamatsu H, et al. (2000): PE
ycsFGI-kipIAR-ycsK	ycsK	ND	ND	ND	Kuwana R, et al. (2002): SDS-PAGE, RG
yfhP	yfhP	`934902..934939`	None	GTTGTACACTAAGGGCACAGTACGATAATATGTTACAT	Fujita M (1999): in-vitro transcription Yamamoto H, et al. (1999): NB RG
yfhP	yfhP	`934890..934928`	None	AGGGCACAGTACGATAATATGTTACATTAAATAGTAATA	Fujita M (1999): in-vitro transcription Yamamoto H, et al. (1999): NB RG
yfnHGFED	yfnE	`800509..800551`	`-37:+6`	GTGAAAGCAAGCGTTATTATTCCTGCATATAATTCGAAGGAGC	Eichenberger P, et al. (2004): Race-PCR
yfnHGFED	yfnH	`797658..797702`	`-39:+6`	TTGGTCACCAAGGCTGGCTTTCTCTCATATCATTACAGTAGATTT	Eichenberger P, et al. (2004): Race-PCR
yhcOP	yhcO	`988970..989019`	`-39:+11`	AATGACACACTGCGAACTCAGGCTGCATAGAGTAAAAATAAAAAGGTACA	Eichenberger P, et al. (2004): Race-PCR
yhjR	yhjR	`1135459..1135513`	`-37:+18`	CTCCGCACATCTCTCCCTGCCCAACATATACTTTTACAGAAGCCCAATTCCTAAG	Eichenberger P, et al. (2004): Race-PCR
yitBA-yisZ	yitB	`1171811..1171855`	`-38:+7`	ACCTGAACCTTTATGCAAAAAATGAATAGTCTGCCTATAACTCGA	Eichenberger P, et al. (2004): Race-PCR
yitCD	yitC	`1171885..1171937`	`-40:+13`	TGCGGAACCATTAAGAGCCCGGCTGAATATGCTTTTTAGCAAAATGGTTTTAT	Eichenberger P, et al. (2004): Race-PCR
yjcB-yjcZ-spoVIF	yjcB	`1252068..1252124`	`-45:+12`	TTTTTGTTTTTTTAACGAGGCGGTCTCGCTCAGCATATATCATAAGCGGGGGGATAA	Kuwana R, et al. (2003): NB DB PE
yjcB-yjcZ-spoVIF	yjcZ	`1252350..1252403`	`-43:+11`	TGCGAATATCCAAGCCGATCCCAGCAGCTCACATAGTGTATAGAGAGTAAAGGA	Kuwana R, et al. (2003): NB DB PE
yjcB-yjcZ-spoVIF	yjcC	`1252626..1252681`	`-45:+11`	ATGTTGGAAAAGCACATTGTATTATGTGCATTCATACAATACCGTATTACTCCGCC	Kuwana R, et al. (2003): NB DB PE
ykuD	ykuD	`1476311..1476371`	`-38:+23`	AATGTAGCAGGATGGGCTCCTCATCAATACTTATAAGTAAAAAAGGAGGATGAGGAAACTG	Eichenberger P, et al. (2004): Race-PCR Kodama T, et al. (2000): NB DB
ykvPQ	ykvP	ND	ND	ND	Kodama T, et al. (2000): NB DB
ylbDE	ylbD	`1566889..1566939`	`-38:+13`	AGGCGAACACAATGCCCGACAAAACGATACATTGTAGTAGGTAACGATTTT	Eichenberger P, et al. (2004): Race-PCR
ymaG	ymaG	ND	ND	ND	Kuwana R, et al. (2002): SDS-PAGE, RG
yndL	yndL	`1914290..1914341`	`-43:+9`	AAAATGAGAAGAACAGCGCCCGGGCTAATGGTATATAATATTGTGAATTTAA	Silvaggi JM, et al. (2006): PE NB DB Eichenberger P, et al. (2004): AR
yngK	yngK	`1958802..1958844`	`-38:+5`	TTAATCACCCTTTTATAGCCCGGGAATACCGTAATAGCGAATA	Eichenberger P, et al. (2004): Race-PCR
yoaN	yoaN	`2038004..2038055`	`-37:+15`	TAGGCACAGCAATCTAAGATTCTGCATAGGCTGAAATAAAATCTTGTTCATT	Costa T, et al. (2004): NB RG HM Eichenberger P, et al. (2004): Race-PCR
yobW	yobW	`2083364..2083415`	`-43:+9`	ATTTCAGCTACTATTTCCGACCGGATAAGCATACACTTCTCAACGGAGGGGA	Henriques AO, et al. (1997): PE HM DB RG
yodHI	yodH	`2132600..2132656`	`-36:+21`	TCATAAACCTATGTCTTTATACGACATATGATAAGGAAAAAGGAGGATTCGATATTG	Eichenberger P, et al. (2004): Race-PCR
ypqA	ypqA	`2336718..2336766`	`-37:+12`	TTTATAACAACATCTGGCATAGACGCATAATCTGGTTAAAAAAGGCGGT	Eichenberger P, et al. (2004): Race-PCR
yqfQ	yqfQ	ND	ND	ND	Kuwana R, et al. (2002): SDS-PAGE, RG
yrkC	yrkC	`2714737..2714787`	`-38:+13`	TTTAGCACACTCCCTTAATAAATGCATAGGATACTATCACAAAAATTTATA	Kuwana R, et al. (2002): SDS-PAGE, RG Eichenberger P, et al. (2004): Race-PCR
ysnD	ysnD	`2896789..2896834`	`-37:+9`	ATAGGCACTTCTCTTGTTCCCTCGGCATACATTAATGATATCTTGC	Eichenberger P, et al. (2004): Race-PCR
ytaA	ytaA	ND	ND	ND	Kuwana R, et al. (2002): SDS-PAGE, RG
ytcC	ytcC	ND	ND	ND	Kuwana R, et al. (2002): SDS-PAGE, RG
ytlABCD	ytlA	`3131335..3131378`	`-36:+8`	GCATTCACACATTTTTATACCCATCATACGATATGTAAAGCAAA	Eichenberger P, et al. (2004): Race-PCR
ywrJ	ywrJ	ND	ND	ND	Kuwana R, et al. (2002): SDS-PAGE, RG
yxeE	yxeE	`4064547..4064594`	`-35:+13`	ATGCGTGCCACTGTGCCAATGACTACATAAGTTATAAGGAATTCACCC	Eichenberger P, et al. (2004): Race-PCR Takamatsu H, et al. (2000): SDS-PAGE