Transcription factor: SigB

Factor type	ND
SWISS-PROT	P06574
SubtiList	BG10735
Consensus seq.	AGGTTT(-35)-N17-GGGTAT(-10)
Comment	RNA Polymerase Sigma-37 Factor (Sigma-B). General stress factor sigma.
Link to	Phylogenetic profile, Weight matrix, Motif alignment & Similar conserved hexameric motifs

Operon	Regulated Gene	Absolute position	Location	Binding seq.(cis-element)	Experimental evidence
aldY	aldY	`3985381..3985421`	None	ATTCGTTTACATATTGGCTTCAGCGGAAATAGAAGAAGACA	Petersohn A, et al. (1999): HB
bmrU-bmr-bmrR	bmrU	`2492786..2492829`	`-40:+4`	TCTTCGTTTACTGCTTACAGAAAAAGGGGATTATATAACCAGAA	Petersohn A, et al. (1999): PE RG
cdd-era	cdd	`2610606..2610659`	`-48:+6`	TTTTTAGAAATGGGCGTGAAAAAAAGCGCGCGATTATGTAAAATATAAAGTGAT	Wang LF, et al. (1984): S1 RO Song BH & Neuhard J (1989): HM
clpP	clpP	`3545117..3545180`	`-45:+19`	CATACGATGGTTTGAACCCCTGTATTTTTGGGGAAAATGGGAAAAAGAGACGACTTTGCATATC	Gerth U, et al. (1998): PE DB HM Voelker U, et al. (1994): 2D PAGE
csbA	csbA	`3614457..3614499`	`-40:+3`	ATGGTGATTGATTTTGGCTGAAAAGGGGTATGGTGTAAGTAGA	Boylan SA, et al. (1991): PE DB RG
csbB	csbB	`930046..930091`	`-43:+3`	AAAAAACAGGTTTAAACGACTTTAAAAAAAGGAATAGCCTTACTGA	Akbar S & Price CW (1996): RG Huang X & Helmann JD (1998): PE RG
csbC	csbC	`4086914..4086968`	None	TTTTCAAAACAAATGTTTCAAATGAGATAGGAAATGGGTACTAATCTATTAACTT	Akbar S, et al. (1999): RG; binding site mutation
ywmF-csbD	csbD	`3769337..3769390`	None	TAACATTAGAATGTTTATTGCCTCTCAGATCGGGAAGTTAACAAGTACACACAT	Akbar S, et al. (1999): RG; binding site mutation
csbX-bofC	csbX	`2838024..2838071`	`-43:+5`	CTAACAGGATTACAATTCAGCAAGCTTGGGTACATACTCCATTGATAC	Gomez M & Cutting SM (1997): PE
gcaD-prs-ctc	ctc	`58706..58747`	`-40:+2`	CGAGGTTTAAATCCTTATCGTTATGGGTATTGTTTGTAATAG	Ollington JF, et al. (1981): NB DP RO, in-vitro transcription Moran CP Jr, et al. (1981): FT S1 RO, dinucleotide priming Tatti KM & Moran CP Jr (1984): RO SDM Igo MM & Losick R (1986): RG NB DP Boylan SA, et al. (1993): RG Voelker U, et al. (1994): 2D PAGE, HB Petersohn A, et al. (1999): HB
ctsR-mcsAB-clpC-radA-yacK	ctsR	`101311..101362`	`-46:+6`	ATCAGCAATCAGGTTTTGTGGACCGGGAAAATGGAAATAATGAAGGATAGAG	Kruger E, et al. (1996): NB PE
dps	dps	`3135740..3135783`	`-41:+3`	AAGAGGTTTTAGCGTACGATATTAAGGGTATACATAGTCATATA	Antelmann H, et al. (1997): 2D-PAGE, NB PE DB
gsiB	gsiB	`493996..494037`	`-38:+4`	TGTTTGTTTAAAAGAATTGTGAGCGGGAATACAACAACCAAC	Maul B, et al. (1995): HB PE DB Mueller JP, et al. (1992): PE RG NB Voelker U, et al. (1994): 2D PAGE, HB
gspA	gspA	`3944465..3944503`	`-37:+2`	ACGTGTTTATTTTTTTGAAAAAGGGTATGTAACTTGTAC	Antelmann H, et al. (1995): PE HB DB NB Petersohn A, et al. (1999): HB
gtaB	gtaB	`3664574..3664616`	`-40:+3`	AAAATGTGTAAAAACATATTGAAAAGGGTAAATAGAGAATAGT	Varon D, et al. (1993): PE DB
katE-yxiS	katE	`4009250..4009293`	`-40:+4`	TAGCAGTTTATATGAAGAACGCCACGGGTAAATGTGCTGTAGAA	Engelmann S, et al. (1995): HB NB DB PE
katX	katX	`3963946..3963999`	`-47:+7`	AAAAAAACGGCTGTTTTAAAATCTTTCCATTCAGGGAATATTGTTACCGTTCAA	Petersohn A, et al. (1999): NB PE DB 2D-PAGE
nadE	nadE	`337773..337823`	`-42:+9`	ACAGTCATGATTCATTTTCATTGATTTAGGGAAATGATCAGTAATAAGGGA	Antelmann H, et al. (1997): NB PE
opuE	opuE	`727777..727821`	`-38:+7`	CAATGTTTCATCGCTTGAATGGCCGGGAATACTTTGTTAGGTTAA	Von Blohn C, et al. (1997): PE DB Spiegelhalter F & Bremer E (1998): NB RG DP SDM
phoPR	phoP	`2977577..2977622`	`-38:+8`	GTTAAGATGACATAAAATAGAGAAATAGGATGTCGGGGAATTATAA	Paul S, et al. (2004): PE, In-vitro reconstitution, DB (unclear result)
relA-yrvI	relA	`2822029..2822072`	`-40:+4`	TTTGCATTTATTTTATATAATATTTGGCTATTTGAACTTCTGCT	Wendrich TM, et al. (1997): PE
rsbRSTUVW-sigB-rsbX	rsbV	`521577..521619`	`-40:+3`	GAAAGGTTTAACGTCTGTCAGACGAGGGTATAAAGCAACTAGT	Kalman S, et al. (1990): PE S1 DB RG Boylan SA, et al. (1993): PE; Western blot; RG Voelker U, et al. (1994): 2D PAGE, HB
trxA	trxA	`2912648..2912689`	`-40:+2`	TCAGGTTTTAAAACAGCTCCGGCAGGGCATGGTAAAGTACAT	Scharf C, et al. (1998): PE, 2D-gel Petersohn A, et al. (1999): HB
yacLMN	yacL	`108556..108597`	`-39:+3`	TTTCGGTTAAAACCTTATGAATACGGGTATATTAATGTTGGT	Petersohn A, et al. (1999): HB PE
gabTD	gabD	`442324..442364`	`-37:+4`	AACGGATTACTTTTGCTGACAGCGGGAATTAACGGTAATAT	Petersohn A, et al. (1999): HB PE
ydaDEFG	ydaD	`471197..471241`	`-40:+5`	AGCCATGTTTATCCAAAGAGTGTGTGAGGTACACAACAAATAGAC	Petersohn A, et al. (1999): PE NB 2D-gel
ydaDEFG	ydaG	`473296..473335`	`-36:+4`	TTGTTTAAATCTTCCCCGGATGTGGAAAAGTAACAGCGGA	Petersohn A, et al. (1999): PE NB 2D-gel
ydaP	ydaP	`488329..488371`	`-39:+4`	TCCGGGTTTTAAAGCCTTTCTCCTGTGGTATTGAAAAAAGGAA	Petersohn A, et al. (1999): PE NB 2D-gel
ydaTS	ydaS	`492488..492529`	None	AAGTGTTTCGAAATGATCAGGAGCGGTTATTGATTGGTAAAT	Petersohn A, et al. (1999): HB
ydaTS	ydaT	`493016..493056`	None	ATGCGTTTTTATTTTTCACCTGCGGGTACCATTTTTATAAA	Petersohn A, et al. (1999): HB
dctB-ydbD	ydbD	`496137..496182`	`-41:+5`	GTTTTTCGTTTATCTTTCTATCGATCGGAAATATAAAAAGAGATAA	Price CW, et al. (2001): RACE-PCR DB
ydbP	ydbP	`507828..507872`	None	CTTTGATTACAGCCAGAGCTGTCTGCAGGGAAACATTATGTTCTG	Petersohn A, et al. (1999): HB
ydfO	ydfO	`596359..596408`	`-45:+5`	AAGACACCGTTTCGTTTTATGAAAACAGGGGAGAACAATTTAAGAGAGAT	Price CW, et al. (2001): RACE-PCR DB
ydhK	ydhK	`623921..623962`	None	TTATGTTTGGCTTTGCAAACAAAGGGGAATAGGACAAACTGC	Petersohn A, et al. (1999): HB
yfhKLM	yfhK	`928069..928111`	None	ACATGTTTCACCAGCCTGTCAATCAGGGAATACCACTTATATC	Antelmann H, et al. (2000): HB
yfkJIH	yfkJ	`861284..861336`	`-44:+9`	TTCATGAAGGTTTCTTTTTAGAGAAATAGGGGCAAAGAATAGGGAGGTTGCAC	Price CW, et al. (2001): RACE-PCR DB
yflA	yflA	`844047..844088`	`-37:+5`	AAAGGTTTATGTTTTTCCATCTATGGGAAATGATTCATAAAC	Petersohn A, et al. (1999): HB PE
yhdF	yhdF	`1021473..1021514`	`-38:+4`	TGGCGTTTATTCATTTCTGTCGTGTGGTAACGTTCAGTATCA	Petersohn A, et al. (1999): HB PE
yhdNO	yhdN	`1029515..1029554`	None	AAGGTTTAACATTTTTTCCAGAGGGGAAAAGATAGTGAAA	Petersohn A, et al. (1999): NB 2D-gel HB
nhaX	nhaX	ND	ND	ND	Pragai Z, et al. (2002): RG
yjbCD	yjbC	`1226177..1226224`	`-42:+6`	TAAGGCTGTTTAAACAAGAAGAAATGGGGTATATCTAAAAGTATGAAG	Petersohn A, et al. (1999): PE HB Antelmann H, et al. (2000): PE NB
yjgB	yjgB	`1284775..1284815`	None	ACATGTTTCGTTGCAAAAACACGGGGAAACGGAATGGTAGA	Petersohn A, et al. (1999): HB
ykgAB	ykgA	`1371206..1371248`	None	AATGGTTTAATGATTTTCATGATGAGGGAATAATAAATGTATT	Petersohn A, et al. (1999): HB
ohrB	ykzA	`1381249..1381304`	`-51:+5`	CTCGGCAAACATAGCATGTTTAAAAAGATCAGAAAGGGAAATATAACAACTAGATA	Volker U, et al. (1998): PE HM
yocK	yocK	`2096841..2096890`	None	CGATGTTTCCATGTTTGACAGAAGGCAAAACGGGAAACAGGATAGAAAGG	Petersohn A, et al. (1999): NB 2D-gel HB
yotK	yotK	`2152613..2152655`	None	TCTAGTTTCTCTTTTTAAAAGAGTAGGGTATTGCAAACAACAG	Petersohn A, et al. (1999): HB
yoxA-dacC	yoxA	`2000100..2000140`	None	AACGGTGTTTTTTTATTTGATAGGGGAAAATATAAAATGGA	Petersohn A, et al. (1999): HB
yoxCB-yoaA	yoxC	`2018577..2018617`	None	TTCTGATTAAAAAAACGGATACAGGGTAATGACATAAGAAA	Petersohn A, et al. (1999): HB
ypuBC	ypuB	`2433561..2433602`	None	TGCTGATTATACAAAAAGTGGATTGGGAATGATAAAAGAACA	Petersohn A, et al. (1999): HB
yqgZ	yqgZ	`2563660..2563715`	`-47:+9`	CTGTAAATGGTTTAAATGAAAAATGATCCGGGTAGTTATTCTACAAAGAGATGGTT	Price CW, et al. (2001): RACE-PCR DB
yqhA	yqhA	`2563172..2563216`	None	TTCGGTTTTTCACCTGTCCAGAAACTGGGCTAGCTGGATTCGAAC	Petersohn A, et al. (1999): HB
yqhQP	yqhQ	`2540123..2540164`	None	CTGCGAGTAAAATTTGAAAATAACGGGTATAATGCATGTAGG	Petersohn A, et al. (1999): HB
yqxD-dnaG-sigA	yqxD	`2603292..2603340`	`-41:+8`	ATCCTGGGTTTTTGGCTGTGCCAAAAGGGAATAATGAAAAACAATAGCA	Liao CT, et al. (1999): PE
yqxL	yqxL	`2560701..2560741`	None	ACTGGTTTAGTGACGCGGTTATTGGGCAATTAAAGAATAAA	Petersohn A, et al. (1999): HB
yrvD	yrvD	`2825417..2825458`	None	CCATGTTTAAAACCAGTCTTGATTGGGAAAGTTACCTCAATA	Petersohn A, et al. (1999): HB
ysnF	ysnF	ND	ND	ND	Pragai Z, et al. (2002): RG
ytkL	ytkL	`3009662..3009703`	None	ATAAGTTTTTCAGCTTTTTAAAAAGGGAAAATAAAAAAAACA	Petersohn A, et al. (1999): HB
ytxGHJ	ytxG	`3047087..3047132`	`-41:+5`	AGTACACATGTTTATGATTGAAGAAAACGGGTAAACAGCAGTATAT	Varon D, et al. (1996): PE DB RG, plasmid integration
yvgO	yvgO	ND	ND	ND	Pragai Z, et al. (2002): RG
yvrE	yvrE	`3405593..3405633`	None	AGTGGTTTGGACACCTCTTTGCCGGGAATAACAATATATAG	Petersohn A, et al. (1999): HB
yvyD	yvyD	`3630632..3630680`	`-42:+7`	GATTTATGTTTCAGCAGGAATTGTAAAGGGTAAAAGAGAAATAGATACA	Drzewiecki K, et al. (1998): PE NB DB Eymann C & Hecker M (2001): PE
ywjC	ywjC	`3817855..3817906`	`-44:+8`	AAAAATAGGTTTACGACTTGTCAGCTTTGGGAACTTAGGCTATATAAGACAA	Price CW, et al. (2001): RACE-PCR DB
ywmE	ywmE	`3773591..3773644`	`-48:+6`	TTTTTTATTGGTTTAAAAACAGTTTGGGCGGGAATGATACCCTAAAAAGGGGTT	Price CW, et al. (2001): RACE-PCR DB
ywtG	ywtG	`3692978..3693030`	`-49:+4`	TAAAAAGGTTTAATGGCCGGAAAAAGAGGCTAAAAGATTTCTAAAAAAATCCC	Price CW, et al. (2001): RACE-PCR DB
yxkO	yxkO	`3972317..3972358`	None	TTTTGTTTGAAAAAGAAAAGGGACAGGAAAAATAGGAAAAGA	Petersohn A, et al. (1999): HB
yycD	yycD	`4157968..4158009`	None	GATCGTTTCGGACAGTAACAAGGCGGGAAAAATGCAATAAAA	Petersohn A, et al. (1999): HB