Transcription factor: SigE

Factor type ND
SWISS-PROT P06222
SubtiList BG10235
Consensus seq. (g/t)(c/a)ATATT(-35) - 14bp -CATACA-T(-10), G(g/t)(C/a)AT(A/g)(T/a)(t/c)(-35) - 13bp - (C/a)ATACA(a/c)T(-10)
Comment RNA polymerase sporulation-specific sigma-29 factor. Inactive precursor, processed by SpoIIGA after Tyr-27; synthesized shortly after the start of sporulation but do not become active until after polar division; expression negatively regulated by sigma-K; disappears in the forespore shortly after septation through a SpoIIIE-dependent process, probably by selective degradation of both SigE and SpoIIGA; pro-sigma-E associated with the cytoplasmic membrane in the predivisional sporangium, then accumulated at the mother cell side of the sporulation septum, and mature sigma-E distributed throughout the mother cell cytoplasm; transcription reduced, and probably processing impeded, in hyperosmotic conditions.
Link to Phylogenetic profile, Weight matrix, Motif alignment & Similar conserved hexameric motifs

Operon Regulated Gene Absolute position Location Binding seq.(cis-element) Experimental evidence
asnO asnO 1156447..1156491 -40:+5 ACAAATCAACTATCTGCCTATAGATGCATAAACTTACTAAGGTGC Yoshida K, et al. (1999): NB PE
bdbDC bdbD ND ND ND Kuwana R, et al. (2002): SDS-PAGE, RG
bofA bofA 29703..29743 -39:+2 AGTGGTCTAAACTCCTGGATCTTCTCATAAGCTTGTACTAG Ricca E, et al. (1992): DP
Ireton K & Grossman AD (1992): PE RG DB OV
cotE cotE 1774203..1774245 -40:+3 TAAGTAAAGTTTCTAGGCACCCCTGCATACAATGGAACAGAAA Zheng LB & Losick R (1990): PE S1 RG DP DB
cotJABC-yesJK cotJA 755176..755219 -38:+6 TTAGTCATAATCATGCCTCCTGCCTCATACCTATTAAGGTCATT Henriques AO, et al. (1995): PE DB RG
ctaA ctaA 1558284..1558336 -47:+6 GCCACAAAACACATATTCGCTTACACTTGGAACGTATATAAAATTGCAGCAGT Paul S, et al. (2001): PE DB
Mueller JP & Taber HW (1989): S1
ybaK-cwlD cwlD 156548..156596 -39:+10 GTAATCATATTTCCCGACCCTGTCCCATAGTTATGTAATAACGGACAAG Sekiguchi J, et al. (1995): PE NB DB
cwlJ cwlJ 281949..281997 -37:+12 TCCGTCATCACTTCTGAAGTAATGAAATATGATGAAAAGAGATCAAGGG Ishikawa S, et al. (1998): PE NB RG DB
dacB-spmAB dacB 2423746..2423788 -36:+7 TTATTCATAACTGATGGACATGCGCATAAACTTGTACAAACCA Simpson EB, et al. (1994): PE
Buchanan CE & Ling ML (1992): DB, immunoassay
gerM gerM 2902186..2902232 -39:+8 TTCGGTCTATTTCCTAAAGAGGCTCGTATACATAATAGTACAAACAT Eichenberger P, et al. (2003): AR, 5'-RACE-PCR
glgBCDAP glgB 3170702..3170744 -39:+4 CTTCGAATAAATACTATAAATGAAAACTATGATGTCAGAAAGG Hay RE, et al. (1986): S1, dinucleotide priming
Kiel JA, et al. (1994): RG
mmgABCDE-yqiQ mmgA 2513274..2513316 -39:+4 TCATTCATTCATGCCCGTTTCAAAGCATACATTCATAGAAGAC Bryan EM, et al. (1996): RG OV PE
nucB nucB 2652041..2652085 None TTAAAAATATTCTTCATCAAGCGCCCATACATTGAAATGAACAAA Van Sinderen D, et al. (1995): FT HM
phoB-ydhF phoB 621137..621185 -35:+14 CTAAAACTTCTCATAAAAGAATAACCATTATTTAAGGGTGCCAGTTCAT Chesnut RS, et al. (1991): PE DP
Abdel-Fattah WR, et al. (2005): RG; in-vitro transcription assay
phoPR phoP 2977593..2977642 -43:+7 AAAATAAAATCATGAAACATGTTAAGATGACATAAAATAGAGAAATAGGA Paul S, et al. (2004): PE, In-vitro reconstitution, DB
prkA prkA 972407..972451 -38:+7 CAAAGCATGTATCACGAGATGGCGGCATAGATTGTATCAAAGTAC Eichenberger P, et al. (2003): AR, 5'-RACE-PCR
safA-coxA safA 2845116..2845161 -42:+4 TCCTTTACTCATAACTTCTTTTGTTCAGGCATATGTTGTGAAGAAA Takamatsu H, et al. (1999): PE
spoIID spoIID 3776804..3776846 -39:+4 AGAGTCATATTAGCTTGTCCCTGCCCATAGACTAGACTAGAGT Rong S, et al. (1986): RO S1
yqhV-spoIIIAABCDEFGH spoIIIAA 2536872..2536913 -39:+3 CTTGTCATAAAGTCTGCCTCACATCATACATTTTAAAGAAGC Illing N & Errington J (1991): RG DB PE OV
yqhV-spoIIIAABCDEFGH spoIIIAG 2533240..2533293 -40:+14 AAATAGAAATACAAGCTTCCCAGCGCGCATATATTCTAGAAGAAATGGCTGTCC Stragier P (2003): personal communication: PE RG
spoIIM spoIIM 2450266..2450307 -36:+6 AAGGGCATGTTTTTCTGTTTCTTTCATACAATCTATTAAATC Smith K, et al. (1993): RG DB PE RO, in-vitro transcription, OV
spoIIP-yqxA spoIIP 2633684..2633727 -40:+4 ACAGTTCTACTTCCTCTAGCTTGTTCATAGAGTAATTACTAGAC Frandsen N & Stragier P (1995): RG PE DB OV
spoIVA spoIVA 2386932..2386975 -40:+4 GATGTCATATTCAAATAGGACAACGTCATACACATATAGTGTCC Roels S, et al. (1992): NB RG DB OV PE
spoIVA spoIVA 2387019..2387060 -38:+4 AAAGGAATGAACCTTTCTCCCTTGCATACAAATAGGGAGAAA Roels S, et al. (1992): NB RG DB OV PE
spoIVCA spoIVCA 2654205..2654254 -44:+6 AAAATCTCCTCATTTGGACAAACAGCTGTTACATAGCATTACCCAAGGGG Sato T, et al. (1994): PE S1
spoIVCB-spoIIIC spoIVCB 2652141..2652188 -39:+9 CGGTACAGACACAGACAGCCTCCCGGTCACATACATTTACATATAGGC Kunkel B, et al. (1988): PE RG
spoIVFAB spoIVFA 2856877..2856928 -46:+6 TTCTTGACTAAACCGAATATTTGCCATGGACAAGACATATGATGTACAAACC Cutting S, et al. (1991): PE RG
spoVB spoVB 2828712..2828754 None CTTGTCATGCTTGGACGACATATACGCATATCTTTATTGTATA Popham DL & Stragier P (1991): RG
spoVD spoVD 1583453..1583496 -37:+7 ATCGTTCTACCTGTCCAAATTCAGGCATAAAATGAAACAAGCCT Daniel RA, et al. (1994): RG DB OV PE
murE-mraY-murD-spoVE-murG-murB-divIB-ylxWX-sbp spoVE 1589520..1589562 -37:+6 GGTGACATGTTTATAGATGCCGTGCATATGCTTAAGTAAGGGC Theeragool G, et al. (1993): PE S1 RG DB
Miyao A, et al. (1993): RO, RNAP purification
murE-mraY-murD-spoVE-murG-murB-divIB-ylxWX-sbp spoVE 1589379..1589427 -40:+9 CTGGGAATACAACATGTCAAACGTGTCGATAATGTTGAACAAGCAGTAT Theeragool G, et al. (1993): PE S1 RG DB
Miyao A, et al. (1993): RO, RNAP purification
spoVID-ysxE spoVID 2871851..2871894 -39:+5 CCACTCATATTTTCTCCAGTTCATACATACACCTTTAGTGACAT Beall B, et al. (1993): PE RG DB OV
spoVK spoVK 1873228..1873270 -40:+3 CATGGTTTGTCCACCCCATGTCCGTGAATACAATAAGAAATAA Errington J, et al. (1989): RG
Foulger D & Errington J (1991): PE RG
spoVM spoVM 1654619..1654662 -40:+4 GAGGTACTTTTTCGTTTGCAAAAGGCATATTAATAATGATAAGA Levin PA, et al. (1993): DB PE RG OV
spoVR spoVR 1014865..1014907 -39:+4 ACTATCATCTTTTGTCTGGCGGGCTCATACATTATAGATAAGT Beall B & Moran CP Jr (1994): PE RG DB OV
usd-spoIIID-mbl-flhOP usd 3747880..3747922 -38:+5 TTTAGCATATTCCCAAAAGAATGCTAATACACTGTTACAAACC Kunkel B, et al. (1989): RG DB
Tatti KM, et al. (1991): PE SDM RG DB OV
Decatur A, et al. (1997): RG
yaaH yaaH 25180..25222 -40:+3 ATAAACATGATCAGCGCTTTTCTTTCATACATTGATAGCGATA Kodama T, et al. (1999): NB PE
Kobayashi K, et al. (2001): AR
yabMNOPQ-divIC-yabR yabP 68137..68181 -39:+6 CTTGTTCTAAAAAAACCCCCCACCTCATACAATGCAGTAATAATG Asai K, et al. (2001): NB DB PE
ybaN ybaN 160572..160615 -35:+9 TCGGTTATATTCAATTGTCCATGCTCATAAGATGTAAAACAAGA Eichenberger P, et al. (2003): AR, 5'-RACE-PCR
ycgFG ycgF 334125..334170 -37:+9 TTGTGCATAGCTTGGCCCGTTCCCGAATAAATTGTACAAGTTACAT Eichenberger P, et al. (2003): AR, 5'-RACE-PCR
ydcA ydcA 515204..515250 -40:+7 TACGTACTATTTAAATGGTTTGTCTCATAAACGTGTTACTATAGATA Eichenberger P, et al. (2003): AR, 5'-RACE-PCR
ydcC ydcC 515636..515684 -40:+9 GTCTGCATATTAGGGAAACCCCACTCATATATTTGATAGTGCATTAAGG Kuwana R, et al. (2002): RG
Eichenberger P, et al. (2003): AR, 5'-RACE-PCR
ydhD ydhD ND ND ND Kodama T, et al. (2000): NB DB
yfhS yfhS 936348..936396 -38:+11 TAGCGTATAGTTCTTTTATTTCCACAAACAATAATGGCAAGAACTTTAA Yamamoto H, et al. (1999): PE NB DB
yfnHGFED yfnE 800509..800551 -37:+6 GTGAAAGCAAGCGTTATTATTCCTGCATATAATTCGAAGGAGC Eichenberger P, et al. (2004): Race-PCR
yhaX yhaX 1055941..1055988 -39:+9 GTTGTTCTAAACACAGAGACAGGGTCATATCCTATACACAAGTACAGT Eichenberger P, et al. (2003): AR, 5'-RACE-PCR
Feucht A, et al. (2003): AR DB RG
yhbH yhbH 974441..974486 -40:+6 GTTTGTCAATTAAACGTGCATATGTGCATATGATGAATATAAATCT Eichenberger P, et al. (2003): AR, 5'-RACE-PCR
Feucht A, et al. (2003): AR DB RG
yhcOP yhcO 988970..989019 -39:+11 AATGACACACTGCGAACTCAGGCTGCATAGAGTAAAAATAAAAAGGTACA Eichenberger P, et al. (2004): Race-PCR
yheCD yheC ND ND ND Kuwana R, et al. (2002): SDS-PAGE, RG
yhjR yhjR ND ND ND Kuwana R, et al. (2002): SDS-PAGE RG
yhxC yhxC ND ND ND Kuwana R, et al. (2002): SDS-PAGE, RG
yitCD yitC 1171885..1171937 -40:+13 TGCGGAACCATTAAGAGCCCGGCTGAATATGCTTTTTAGCAAAATGGTTTTAT Eichenberger P, et al. (2004): Race-PCR
yjbE yjbE ND ND ND Feucht A, et al. (2003): AR DB RG
yjbX yjbX 1247921..1247969 -39:+10 TTTCTTCTGATTTTCAGCTTTCTGTCATATAGATAGAATATGACACAAT Eichenberger P, et al. (2003): AR, 5'-RACE-PCR
Feucht A, et al. (2003): AR DB RG
yjcA yjcA 1251416..1251466 -45:+6 CAAGATACAATTCATGAAGAATAGGGTTTTGGCATATATGTGAAGGGATCA Kuwana R, et al. (2003): NB DB PE
yjdH yjdH ND ND ND Kuwana R, et al. (2002): SDS-PAGE, RG
yjfA yjfA ND ND ND Kuwana R, et al. (2002): SDS-PAGE, RG
uxaC-yjmBCD-uxuA-yjmF-exuTR-uxaBA yjmC 1302632..1302680 -46:+3 TATAATATAAAGAATATTTAAAATAATTTGTAAATAAAATGTGTTTGTA Mekjian KR, et al. (1999): PE RG
yknT yknT 1494690..1494737 -42:+6 AGAGGAATAGCTGTTCAGTATTTGCATATTGTAGTGTTAACATCATGA Henriques AO, et al. (1997): PE HM OV DB RG
ykvI ykvI 1437320..1437362 -34:+9 TTCGTCTTTTCAAGGAACTTGTCTCATAGGTTATAAAAAGGCA Eichenberger P, et al. (2003): AR, 5'-RACE-PCR
ykvUV ykvU 1448494..1448540 -39:+8 AATAAAATAATTTTTGAACTTGTCTCATATGATGTTGGTAGTACAAG Eichenberger P, et al. (2003): AR, 5'-RACE-PCR
ylbJ ylbJ 1571198..1571245 -39:+9 TATGGTCTAAACTGAACCCCTATGCTCGTATATTAGTACAAAGAATCA Eichenberger P, et al. (2003): AR, 5'-RACE-PCR
gerR ylbO ND ND ND Juan Wu L, et al. (2000): RG DB
Feucht A, et al. (2003): AR DB RG
yloB yloB ND ND ND Feucht A, et al. (2003): AR DB RG
Raeymaekers L, et al. (2002): Western blotting
yncD yncD ND ND ND Feucht A, et al. (2003): AR DB RG
yndA yndA ND ND ND Feucht A, et al. (2003): AR DB RG
yngJIHGFE yngJ 1956582..1956630 -38:+11 CAGGGAATGATTATAGAACTCGCCTAATAGGATGTTACAAAGATGTGAA Eichenberger P, et al. (2003): AR, 5'-RACE-PCR
yoaW yoaW 2046885..2046927 -39:+4 GCCTGAATATTTCTTTGAGCTAATGAATACAATAAATCGATAG Rather PN, et al. (1986): S1 RO
ypjB ypjB 2361549..2361595 -39:+8 GTTGGTCTATCCTTGTCCCTTTCTTCATATTCTGTAAGGAGAGAGAG Eichenberger P, et al. (2003): AR, 5'-RACE-PCR
ypqA ypqA 2336718..2336766 -37:+12 TTTATAACAACATCTGGCATAGACGCATAATCTGGTTAAAAAAGGCGGT Eichenberger P, et al. (2004): Race-PCR
yqfCD yqfC 2616187..2616238 -40:+12 AAAGTGTTAGAACCTCCTTTCAAATCATACACATGAGATGAAAGGGGGTTCT Eichenberger P, et al. (2003): AR, 5'-RACE-PCR
yqfZY yqfZ 2587869..2587918 -38:+12 TTTGTCATGAATCGAAATGGACAAGCATACTATGGTATAAAATTTCGTAT Eichenberger P, et al. (2003): AR, 5'-RACE-PCR
yrrRS yrrR ND ND ND Wei Y, et al. (2004): RG DB
ysnD ysnD ND ND ND Kuwana R, et al. (2002): SDS-PAGE, RG
yteV yteV 3077636..3077679 -37:+7 TCTATCATAACGCTGTTCCAAACGGAATAGATTGATAGAGAAAG Henriques AO, et al. (1997): PE HM OV DB RG
ytrHI ytrH 2993741..2993787 -35:+12 ATCATCATACTTGTCCTGAAAGCTCAATATGATATAAAAGGTGAGGT Eichenberger P, et al. (2003): AR, 5'-RACE-PCR
ytvI ytvI 2982132..2982178 -33:+14 GTATTCATATTCAGCCGCAGCGTGAATACATATAAAAAATAGGACAT Eichenberger P, et al. (2003): AR, 5'-RACE-PCR
ytxC ytxC 2961487..2961533 -39:+8 TTACGTCTATTTTAAAAACATCCCCCATATACTTGTAACAGATGCCG Eichenberger P, et al. (2003): AR, 5'-RACE-PCR
yunB yunB 3322261..3322309 -38:+11 CTATTACTATGTCCCCTCTTACAAGCATACATTGTGATATGTAAGGGGG Eichenberger P, et al. (2003): AR, 5'-RACE-PCR
yuzC yuzC 3256673..3256722 -37:+13 TTTGTCATATTCGGCAATTAGGGATCTATACATATAGAAACATCCTTTTT Eichenberger P, et al. (2003): AR, 5'-RACE-PCR
Kuwana R, et al. (2002): SDS-PAGE, RG
ctpB yvjB ND ND ND Pan Q, et al. (2003): RG DB, gfp assay
ywdL ywdL 3892296..3892348 -46:+7 GTTCTTTTTCAGCATAATCCAAGCATCAGCCTCATAAGGTGAAAGAGATAAAA Ragkousi K, et al. (2003): PE RG
yxjC-scoAB-yxjF yxjC 4003222..4003263 -36:+6 ATCGGAATAGTTGGCCCACGCTTCTCGTACATATGGAAAGGG Eichenberger P, et al. (2003): AR, 5'-RACE-PCR
yyaD yyaD 4203495..4203539 -39:+6 TATGGCATGTTTGCTTTCCTTTATTTATATAGTAACAATAACGGG Eichenberger P, et al. (2003): AR, 5'-RACE-PCR
yybHI yybI 4176732..4176777 -37:+9 TATGTCTTTGATGTGCCATTCCTGCATATAATGATTCATTCAGCTG Eichenberger P, et al. (2003): AR, 5'-RACE-PCR



Copyright: Human Genome Center, Inst. Med. Sci., Univ. Tokyo; 1999-2006
Contact: Kenta Nakai